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Xalatan vs. Zioptan

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Latanoprost (Xalatan) and Zioptan (tafluprost) are both prostaglandin eye drops used to lower eye pressure in conditions like open-angle glaucoma and ocular hypertension. Latanoprost needs to be refrigerated until opened, but can then be stored at room temperature for up to 6 weeks. Zioptan must be kept in the fridge until the foil pouch is opened and then used within 30 days. Zioptan is preservative-free, which may be less irritating for your eyes, but makes it more likely to be contaminated with germs and cause an infection. On the other hand, latanoprost contains the preservative, benzalkonium chloride, which can damage soft contact lenses. If you wear soft contacts, remove them before using and wait 15 minutes before putting them back in. Both medications can cause changes in eye color and eyelash growth, but latanoprost is more likely to cause eye irritation and inflammation. Latanoprost can trigger herpes infections in the eye, which isn’t observed for Zioptan. Additionally, both medications are available in generic forms, making it more affordable than brand name varieties.

Latanoprost

(Xalatan)

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Zioptan

(tafluprost)

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Summary for Xalatan

Prescription only

Latanoprost (Xalatan) is an eye drop medication. It's used in adults to treat conditions related to high pressure in the eye, such as glaucoma. It works as a prostaglandin to help with high eye pressure. The typical dosage is 1 drop in the affected eye(s) once each night. Side effects include feeling like there's something in the eye, burning, and stinging. Unopened bottles need to be refrigerated. But once opened, you keep the medication at room temperature. Latanoprost (Xalatan) is available as a brand-name and generic medication.

Indications for Xalatan

Pros and Cons for Xalatan

Pros

Cons

  • Can permanently change the color of your eye
  • Need to take out any soft contact lenses before using

Common Side Effects for Xalatan

  • Feeling like there's something inside the eye (13%)
  • Stinging (9%)
  • Eye redness (8%)
  • Blurry vision (8%)
  • Itchy eye (8%)
  • Burning (7%)
  • Changes in eye color (7%)

Warnings for Xalatan

  • Darker eyes or eyelids
  • Eyelash changes
  • Eye inflammation
  • Swelling of the retina (macular edema)
  • Caution use in people with a history of a herpes eye infection
  • Risk of bacterial eye infection when using contaminated medication
  • Don't use while wearing soft contact lenses

Summary for Zioptan

Prescription only

Zioptan (tafluprost) is an eye drop medication used to treat high pressure in the eye, such as glaucoma. It works as a prostaglandin to help relieve pressure in the eye. Zioptan (tafluprost) is for adults and is used once each night. Side effects include feeling like there's something in the eye, burning, and stinging. Zioptan (tafluprost) is available as a brand-name and now also a generic medication.

Indications for Zioptan

Pros and Cons for Zioptan

Pros

  • A first-choice option for lowering eye pressure
  • Only used once a day
  • Is preservative free, which might be less irritating to the eye

Cons

  • Often causes some eye redness
  • Can permanently darken the color of your eye over time
  • Must use eye drop vials inside the foil pouch within 30 days after opening the pouch

Common Side Effects for Zioptan

  • Eye redness (up to 20%)
  • Eye stinging or irritation (7%)
  • Headache (6%)
  • Itchy eye (5%)

Warnings for Zioptan

  • Darker eyes or eyelids
  • Eyelash changes
  • Eye inflammation
  • Swelling of the retina (macular edema)

Prices with our coupons for Xalatan vs. Zioptan

Price Card Drug Icon
Latanoprost1 eye dropper / 2.5ml of 0.005%
$13.85$18.94
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Price Card Drug Icon
Tafluprost1 carton / 30 single-use containers of 0.0015%
$60.48$233.00
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