Compare Xalatan vs. Zioptan

Latanoprost (Xalatan) and Zioptan (tafluprost) are both prostaglandin eye drops used to lower eye pressure in conditions like open-angle glaucoma and ocular hypertension. Latanoprost needs to be refrigerated until opened, but can then be stored at room temperature for up to 6 weeks. Zioptan must be kept in the fridge until the foil pouch is opened and then used within 30 days. Zioptan is preservative-free, which may be less irritating for your eyes, but makes it more likely to be contaminated with germs and cause an infection. On the other hand, latanoprost contains the preservative, benzalkonium chloride, which can damage soft contact lenses. If you wear soft contacts, remove them before using and wait 15 minutes before putting them back in. Both medications can cause changes in eye color and eyelash growth, but latanoprost is more likely to cause eye irritation and inflammation. Latanoprost can trigger herpes infections in the eye, which isn’t observed for Zioptan. Additionally, both medications are available in generic forms, making it more affordable than brand name varieties.