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Compare Zioptan vs. Pilocarpine

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Zioptan (tafluprost)
    Pilocarpine (Salagen)
  • Zioptan (tafluprost)
    Pilocarpine (Salagen)

  • Summary of Zioptan vs. Pilocarpine

    Summary for Prostaglandin
    Prescription only

    Zioptan (tafluprost) is an eye drop medication used to treat high pressure in the eye, such as glaucoma. It works as a prostaglandin to help relieve pressure in the eye. Zioptan (tafluprost) is for adults and is used once each night. Side effects include feeling like there's something in the eye, burning, and stinging. Zioptan (tafluprost) is available as a brand-name and now also a generic medication.

    Summary for Cholinergic agonist
    Prescription only

    Pilocarpine (Salagen) is a cholinergic agonist that's used to help certain adults with dry mouth. It's a tablet that's taken by mouth 3 to 4 times per day. Side effects can include sweating, nausea, and runny nose. It's important to tell your provider and pharmacist about your medical history and your other medications because pilocarpine (Salagen) can sometimes worsen certain medical conditions and interact with many different medications.

  • Indications of Zioptan vs. Pilocarpine

    Indications for
    •High pressure in the eye in people with open-angle glaucoma or ocular hypertension
    Indications for
    •Dry mouth due to radiation therapy for head and neck cancer
    •Dry mouth due to Sjögren's syndrome

  • Pros and Cons of Zioptan vs. Pilocarpine

    Pros and Const for Prostaglandin
    Pros
    •A first-choice option for lowering eye pressure
    •Only used once a day
    •Is preservative free, which might be less irritating to the eye
    Cons
    •Often causes some eye redness
    •Can permanently darken the color of your eye over time
    •Must use eye drop vials inside the foil pouch within 30 days after opening the pouch
    Pros and Const for Cholinergic agonist
    Pros
    •Works well to help with dry mouth
    •Can start to work quickly (about 20 minutes)
    •Available as a lower-cost, generic medication
    Cons
    •Need to take 3 or 4 times a day
    •Can take several weeks to get the most benefit from the medication
    •Can have a lot of side effects since the medication can reach and affect many parts of your body

  • Common Side Effects of Zioptan vs. Pilocarpine

    Common Side Effects for
    •Eye redness (up to 20%)
    •Eye stinging or irritation (7%)
    •Headache (6%)
    •Itchy eye (5%)
    Common Side Effects for

    Treatment of dry mouth from radiation:

    •Sweating (up to 68%)
    •Nausea (up to 15%)
    •Chills (up to 15%)
    •Runny nose (up to 14%)
    •Flushing (up to 13%)
    •Frequent urination (up to 12%)
    •Weakness (up to 12%)
    •Dizziness (up to 12%)

    Treatment of dry mouth from Sjögren's syndrome:

    •Sweating (40%)
    •Frequent urination (10%)
    •Flushing (9%)
    •Chills (4%)

  • Warnings of Zioptan vs. Pilocarpine

    Common Side Effects for
    •Darker eyes or eyelids
    •Eyelash changes
    •Eye inflammation
    •Swelling of the retina (macular edema)
    Common Side Effects for
    •Possible worsening of medical conditions
    •Vision changes
    •Dose too high

  • Prices with our coupons for Zioptan vs. Pilocarpine

    Learn more about Zioptan
    Learn more about Pilocarpine

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