Key takeaways
Bupropion (Wellbutrin XL, Wellbutrin SR) and alprazolam (Xanax) are both prescription medications used for mental health conditions, but they have important differences. Bupropion is an atypical antidepressant used to treat depression and seasonal affective disorder (SAD), while alprazolam is a benzodiazepine used for generalized anxiety disorder (GAD) and panic disorder. Bupropion is available in various forms, including immediate-release, sustained-release, and extended-release tablets, and is not a controlled substance. In contrast, alprazolam is a V controlled medication, typically taken three times a day, and is meant for short-term use due to the risk of dependence. Bupropion can cause side effects like headaches and trouble sleeping, and it has a risk of seizures, especially if you have a history of seizures or eating disorders. Alprazolam can cause drowsiness and memory problems and should not be mixed with alcohol or opioids due to the risk of severe sedation and breathing problems. Both medications are available as a lower-cost generic.
