Key takeaways
Vivitrol (naltrexone) and Narcan (naloxone) are both opioid antagonists, but they serve different purposes and are used in different ways. Vivitrol is an extended-release injection given once a month to help treat opioid and alcohol use disorders by blocking the feel-good effects of these substances, thus reducing cravings. It is only available by prescription and must be administered by a healthcare professional. On the other hand, Narcan is used to reverse the effects of an opioid overdose and can be administered as a nasal spray or injection. Narcan works quickly, within 2 to 3 minutes, but its effects last only 30 to 90 minutes, so it's crucial to seek emergency medical help immediately after use. Unlike Vivitrol, Narcan is available over-the-counter and can be used by anyone in an emergency situation. While Vivitrol is used as part of a long-term treatment plan, Narcan is a life-saving emergency treatment.
