Opioid overdose occurs when excessive amounts of narcotics are ingested. It is a leading cause of accidental death. Symptoms include slowed or even stopped heart rate and breathing, and decreased level of consciousness.
Opioid antagonists like naloxone are effective at reversing the effects of the overdose, not just treating the symptoms. Naloxone, even given immediately at home, isn't a substitute for medical care - if you suspect an overdose, contact emergency services.