Key takeaways
Testosterone oral tablet (Striant) and Testopel (testosterone pellets) are both testosterone replacement therapies used to treat low testosterone in adult males. However, they differ in several ways. Striant, which is no longer available in the U.S., was an orally dissolving tablet. Testopel is a pellett that's implanted under the skin. Testopel is also used for delayed puberty, which is not an indication for Striant. Testopel is implanted under the skin every 3 to 6 months, providing long-acting testosterone release, while Striant required more frequent dosing. Testopel can cause side effects like pain and swelling at the implantation site, and it has risks such as infection and extrusion, which were not concerns with Striant. Additionally, Testopel has interactions with blood thinners like warfarin, which may require monitoring.
