Key takeaways
Trospium and Toviaz (fesoterodine) are both medications used to treat overactive bladder (OAB) in adults, but they have key differences. Trospium is an antimuscarinic medication available as immediate-release tablets taken twice daily or extended-release capsules taken once daily. Toviaz is an anticholinergic urinary antispasmodic available only as an extended-release tablet taken once daily. Trospium must be taken on an empty stomach, whereas Toviaz can be taken with or without food. Toviaz is also approved to treat neurogenic detrusor overactivity (NDO) in children aged 6 years and older, while trospium has not been studied in kids. Both medications can cause dry mouth and constipation, but Toviaz has a higher incidence of dry mouth compared to trospium. Additionally, Toviaz interacts with many medications, which may require dose adjustments, while trospium has fewer noted interactions. Both medications are available in lower-cost generic forms.
