Key takeaways
Nabumetone (Relafen) and naproxen (Naprosyn) are both nonsteroidal anti-inflammatory drugs (NSAIDs) used to treat pain and inflammation, but they have some differences. Nabumetone is typically taken once a day, while naproxen is usually taken twice a day. Nabumetone is known to cause fewer stomach-related side effects compared to naproxen, but both medications can cause stomach bleeding and ulcers. Naproxen is available in both prescription and over-the-counter forms, while nabumetone is only available by prescription. Additionally, naproxen is used for a wider range of conditions, including gout and menstrual cramps, whereas nabumetone is mainly used for rheumatoid arthritis and osteoarthritis. Both medications can raise your risk of heart attack, stroke, and kidney problems. Always consult a healthcare professional to determine which medication is best for you.
