Key takeaways
Diclofenac (Voltaren) and nabumetone (Relafen) are both prescription NSAIDs used to treat pain and inflammation, but they have some key differences. Diclofenac is available in various formulations, including tablets, capsules, and powder, and is used for a wider range of conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, migraines, and menstrual cramps. Nabumetone, on the other hand, is typically used for osteoarthritis and rheumatoid arthritis and can be taken once a day, which can be more convenient. Both medications have a risk of serious side effects like heart attack, stroke, and stomach bleeds, especially with long-term use. Neither medication is recommended during pregnancy, especially in the later stages, and should not be combined with other NSAIDs. Both medications are available in generic forms, making them potentially more affordable options.
