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Provigil vs. Desoxyn

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Modafinil (Provigil) and methamphetamine (Desoxyn) are both prescription medications, but they serve different purposes and belong to different drug classes. Modafinil is a wakefulness-promoting agent used to treat excessive sleepiness due to narcolepsy, obstructive sleep apnea, or shift work disorder. Methamphetamine, on the other hand, is a stimulant primarily used to treat attention deficit-hyperactivity disorder (ADHD) in people aged 6 years and older. Modafinil is taken once daily, while methamphetamine might need to be taken once or twice a day. Modafinil is a Schedule IV controlled substance, indicating a lower potential for misuse compared to methamphetamine, which is a Schedule II controlled substance with a higher risk of addiction and dependence. Common side effects of modafinil include headache and nausea, whereas methamphetamine can cause high blood pressure, fast heartbeat, and low appetite. Additionally, methamphetamine is not recommended during pregnancy or breastfeeding due to potential harm to the baby, while modafinil's safety in these conditions is also uncertain.

Modafinil

(Provigil)

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Methamphetamine

(Desoxyn)

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Summary for Provigil

Prescription only

Modafinil (Provigil) helps improve wakefulness in adults with narcolepsy, obstructive sleep apnea, or shift work disorder. This wake-promoting medication comes as a tablet that’s taken by mouth. For adults with narcolepsy or sleep apnea, you take a dosage once daily in the morning. And for those with shift work disorder, you take your dosage 1 hour before the start of your work shift. Common side effects include headache and nausea. Modafinil (Provigil) is a controlled substance because of its potential for misuse.

Indications for Provigil

Pros and Cons for Provigil

Pros

Cons

Common Side Effects for Provigil

  • Headache (34%)
  • Nausea (11%)
  • Feeling nervous (7%)
  • Runny nose (7%)
  • Back pain (6%)
  • Diarrhea (6%)
  • Anxiety (5%)
  • Dizziness (5%)
  • Indigestion (5%)
  • Trouble sleeping (5%)

Warnings for Provigil

  • Serious allergic reactions
  • Serious rash and skin reactions
  • Sleepiness and trouble focusing, thinking, and reacting
  • Unusual changes in mood and behavior
  • Heart problems
  • Changes in blood pressure and heart rate

Summary for Desoxyn

Prescription only

Methamphetamine (Desoxyn) is a stimulant medication. It's FDA-approved to treat attention deficit-hyperactivity disorder (ADHD), but it's not commonly prescribed because other options are preferred. Some side effects of methamphetamine (Desoxyn) include restlessness, high blood pressure, and low appetite. Methamphetamine (Desoxyn) is a controlled substance with a risk of addiction and dependence.

Indications for Desoxyn

Pros and Cons for Desoxyn

Pros

  • Possible option for ADHD when other medications haven't worked
  • Taken by mouth
  • Available as a generic medication

Cons

  • Only available as a tablet
  • Might need to take twice daily
  • Not safe during pregnancy or breastfeeding

Common Side Effects for Desoxyn

  • High blood pressure
  • Fast heartbeat
  • Tremors
  • Trouble sleeping
  • Dizziness
  • Diarrhea or constipation
  • Low appetite
  • Dry mouth
  • Weight loss

Warnings for Desoxyn

  • Addiction, misuse, and dependence
  • Serious heart problems
  • Changes in behavior or thoughts
  • Seizures
  • Blood circulation problem (Raynaud's phenomenon)
  • Slowed growth in children
  • Serotonin syndrome
  • Worsening of motor and verbal tics

Prices with our coupons for Provigil vs. Desoxyn

Price Card Drug Icon
Modafinil30 tablets / 200mg
$22.28$136.82
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Methamphetamine60 tablets / 5mg
$146.59$1,063.92
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