Premarin vs. Estrace for Osteoporosis and Menopause: Important Differences and Potential Risks.

Premarin tablet

estradiol tablet

Summary for Premarin

Prescription only

Premarin (conjugated estrogens) oral tablet is an estrogen hormone replacement therapy (HRT) used to treat menopause symptoms, such as hot flashes and vaginal dryness, and other conditions caused by low estrogen levels. It can also help prevent osteoporosis after menopause and treat certain advanced breast or prostate cancers. Depending on why you're taking it, you might take it by mouth every day or in cycles. Common side effects include headache, stomach pain, nausea, and breast pain.

Indications for Premarin

Hot flashes, night sweats, and flushes caused by menopause
Vaginal dryness caused by menopause
Low estrogen levels due to certain conditions
Advanced breast cancer
Advanced prostate cancer
Prevention of bone loss (osteoporosis) after menopause

Pros and Cons for Premarin

Pros

Relieves multiple menopause symptoms
Available in multiple strengths
Comes as a tablet that you take by mouth

Cons

Raises your risk of blood clots, stroke, and certain cancers
Some people might need to take it with another hormone called progestin
Can cause vaginal bleeding and spotting

Common Side Effects for Premarin

Headache (13-14%)
Abnormal vaginal bleeding (2-13%)
Breast pain (7-12%)
Stomach pain (8-11%)
Passing gas (4-6%)
Vaginal discharge (4-5%)
Back pain (3-5%)
General pain (3-5%)
Nausea (3-5%)
Insomnia (3-5%)
Depression (3-5%)
Weakness (2-5%)

Warnings for Premarin

Blood clots, heart attacks, and strokes
Uterine (endometrial) cancer
Breast cancer
Dementia
Ovarian cancer
Liver or gallbladder problems
Changes in calcium levels in the blood
Vision problems
High triglycerides (fat) levels
Low thyroid hormone levels
Buildup of fluids in your body (fluid retention)
Worsening of certain other health conditions

Summary for Estrace

Prescription only

Estradiol tablet is an estrogen hormone used to treat menopause symptoms like hot flashes, night sweats, and vaginal irritation. It also helps prevent bone loss (osteoporosis) after menopause. Though not as common, it's also FDA approved to treat certain advanced stages of breast and prostate cancer. The dose depends on your condition, but tablets are typically taken by mouth 1 to 3 times a day. Common side effects include nausea, vomiting, headache, and breast pain.

Indications for Estrace

Hot flashes, night sweats, and flushes caused by menopause
Vaginal dryness caused by menopause
Low estrogen levels due to certain conditions
Certain advanced stages of breast cancer
Certain advanced stages of prostate cancer
Prevention of bone loss (osteoporosis) after menopause

Pros and Cons for Estrace

Pros

Relieves multiple menopausal symptoms
Available in many strengths, allowing you to customize your dose
Comes as a tablet that you take by mouth

Cons

Raises your risk of certain cancers, blood clots, and strokes
Some people might need to take it with another hormone called progestin
Not a first-choice medication for treating bone loss after menopause

Common Side Effects for Estrace

Headache
Breast pain
Abnormal vaginal bleeding or spotting
Stomach cramps or bloating
Nausea
Vomiting
Hair loss

Warnings for Estrace

Uterine (endometrial) cancer
Breast cancer
Blood clots and strokes
Heart disease and heart attacks
Dementia
Gallbladder and liver problems
Vision problems
High triglycerides
Low thyroid hormone levels (hypothyroidism)
Fluid Retention
Changes in calcium levels in the blood
Worsening of other health conditions

Prices with our coupons for Premarin vs. Estrace

Premarin30 tablets / 0.625mg

$99.00$261.42

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Estradiol90 tablets / 1mg

$20.22$71.62

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Premarin vs. Estrace

Premarin tablet

estradiol tablet

Summary for Premarin

Indications for Premarin

Pros and Cons for Premarin

Pros

Cons

Common Side Effects for Premarin

Warnings for Premarin

Summary for Estrace

Indications for Estrace

Pros and Cons for Estrace

Pros

Cons

Common Side Effects for Estrace

Warnings for Estrace

Prices with our coupons for Premarin vs. Estrace

Compare other Osteoporosis and Menopause drugs

Browse medications by letter

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Premarin tablet

estradiol tablet

Summary for Premarin

Indications for Premarin

Pros and Cons for Premarin

Pros

Cons

Common Side Effects for Premarin

Warnings for Premarin

Summary for Estrace

Indications for Estrace

Pros and Cons for Estrace

Pros

Cons

Common Side Effects for Estrace

Warnings for Estrace