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Prednisone vs. Cimzia

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Prednisone (Rayos, Prednisone Intensol) and Cimzia (certolizumab pegol) are both used to treat conditions related to the immune system, but they work in different ways and are used for different types of conditions. Prednisone is an oral corticosteroid that helps reduce inflammation and is used for a wide range of conditions, including autoimmune disorders, allergies, skin conditions, and certain cancers. It is available in generic form and can be taken as a tablet or oral liquid. Common side effects include stomach irritation, insomnia, and weight gain. On the other hand, Cimzia is an injectable tumor necrosis factor (TNF) blocker used to treat autoimmune conditions like rheumatoid arthritis, Crohn's disease, and psoriasis. It is not available in a generic form and is administered every 2 to 4 weeks. Side effects of Cimzia include upper respiratory infections, urinary tract infections, and skin rash. While both medications can increase the risk of infections, Cimzia also carries a risk of heart failure and certain cancers. Prednisone is more likely to cause mood and behavior changes, as well as long-term issues like weakened bones and eye problems.

Prednisone

 

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Cimzia

(certolizumab)

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Summary for Prednisone

Prescription only

Prednisone is an oral corticosteroid. It's taken by mouth by adults and children to treat health conditions related to an overactive immune system or inflammation, such as allergies and certain skin conditions. Your healthcare team will determine your dose based on what medical condition you have. Some of the common short-term side effects of prednisone include stomach irritation and mood changes. And if you take this medication for a month or longer, you're more likely to experience long-term side effects, like weight gain and weakened immune system.

Indications for Prednisone

This medication is used for many different conditions. Generally, it's used for autoimmune problems, conditions related to swelling, or cancer. Some examples include:

Pros and Cons for Prednisone

Pros

  • Works well to treat many different conditions involving the immune system
  • Available as a liquid, which is a good option for people who have difficulty swallowing pills
  • Available as a lower-cost generic
  • Dose can be adjusted based on your response to the medication

Cons

  • Can cause side effects like upset stomach, mood changes, and sleep problems
  • Need to taper your dose before stopping (if you took it for more than a couple of weeks)
  • Might raise your risk for infections, bone weakening, and skin problems if used long term
  • Can slow growth in children if they take it for a long period of time

Common Side Effects for Prednisone

  • Swelling (e.g., puffiness in the face, hands, or feet)
  • Stomach bloating
  • Muscle weakness
  • Headache
  • Insomnia (trouble sleeping)
  • Changes in your mood
  • Larger appetite (possibly leading to weight gain)
  • Higher blood sugar

Warnings for Prednisone

  • Greater risk of infections
  • Mood and behavior changes
  • Reduced adrenal gland function
  • Changes in heart and kidney function
  • Stomach problems
  • Bone problems with long-term use
  • Eye problems with long-term use

Summary for Cimzia

Prescription only

Cimzia (certolizumab) is a prescription biologic used to treat several autoimmune conditions, like rheumatoid arthritis, psoriatic arthritis, and Crohn's disease. It works by blocking a protein called tumor necrosis factor (TNF), which helps reduce inflammation in your body. The medication is given as an injection under the skin every 2 to 4 weeks, depending on your condition. Common side effects include upper respiratory infections, urinary tract infections (UTIs), and skin rash.

Indications for Cimzia

Pros and Cons for Cimzia

Pros

  • Treats a variety of autoimmune conditions
  • Only need to inject every 2 to 4 weeks
  • Available as a prefilled syringe for at-home administration

Cons

  • Can raise your risk for infections
  • Some people might have difficulty injecting it properly
  • Might have a higher risk for certain cancers

Common Side Effects for Cimzia

Warnings for Cimzia

  • Serious infections
  • Cancer
  • Heart failure
  • Allergic reactions
  • Nervous system problems
  • Blood problems
  • Lupus-like condition
  • Live vaccines

Prices with our coupons for Prednisone vs. Cimzia

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Prednisone10 tablets / 20mg
$8.95-
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Cimzia1 carton / 2 prefilled syringes of 200mg/ml
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