Key takeaways
Clopidogrel (Plavix) and ticlopidine (Ticlid) are both antiplatelet medications used to prevent blood clots. They work by stopping platelets in your blood from clumping together. However, there are several differences between the two. Ticlopidine has been discontinued in the United States and is no longer available. Clopidogrel is taken once daily, typically at a dose of 75 mg, and is used for preventing heart attacks, strokes, and in people with peripheral artery disease. Clopidogrel can cause side effects like bleeding and bruising, and it interacts with many medications, such as certain antidepressants and NSAIDs. Ticlopidine was discontinued partly due to its risk of serious blood problems, and safer alternatives such as clopidogrel are now preferred.
