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Loprox vs. Jublia

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Ciclopirox (Loprox, Penlac) and Jublia (efinaconazole) are both prescription antifungal medications, but they have some key differences. Ciclopirox is available in various forms, including cream, gel, shampoo, suspension, and nail lacquer, and can treat a wide range of fungal infections on the skin, nails, and scalp. In contrast, Jublia is only available as a topical solution specifically for treating toenail fungus. Ciclopirox has a generic version, making it a more affordable option, while Jublia is only available as a brand-name medication. Treatment duration also varies: ciclopirox nail lacquer can take up to a year to show results, similar to Jublia, which requires daily application for 11 months. Additionally, ciclopirox requires weekly removal of the nail lacquer with rubbing alcohol, whereas Jublia does not. Both medications should not be used with nail polish, but Jublia is flammable and should be kept away from open flames.

Ciclopirox

 

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Jublia

(efinaconazole)

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Summary for Loprox

Prescription only

Ciclopirox is an antifungal medication that treats different fungal infections on your skin, scalp, or nails. It comes in several forms, like a cream, gel, shampoo, suspension, or solution (nail lacquer). You apply it directly to the infected area, and the dose depends on what you’re treating. Side effects include skin irritation, burning, or itching at the application site.

Indications for Loprox

Pros and Cons for Loprox

Pros

  • Available in several forms for different areas of the body
  • Treats a variety of fungal infections
  • Easy to use and can be applied right where you need it

Cons

  • Not for use in young children
  • Can take weeks to months to fully clear the infection
  • Not a good choice for serious or complicated fungal infections

Common Side Effects for Loprox

  • Redness or irritation at the site of application
  • Burning or itching

Warnings for Loprox

  • Skin irritation

Summary for Jublia

Prescription only

Jublia (efinaconazole) is a prescription antifungal medication used to treat toenail fungus in people 6 years and older. It comes as a topical solution that you apply once a day directly to the affected toenail and the skin around it. Treatment usually lasts for almost a year. Common side effects include ingrown toenail and redness, itching, or irritation at the application site.

Indications for Jublia

Pros and Cons for Jublia

Pros

  • Used just once a day
  • Applied directly to the toenail(s)
  • Fewer side effects compared to oral antifungals

Cons

Common Side Effects for Jublia

  • Ingrown toenail (2%)
  • Skin irritation around the application site (2%)
  • Blisters around the application site (2%)

Prices with our coupons for Loprox vs. Jublia

Price Card Drug Icon
Ciclopirox1 bottle / 6.6ml of 8%
$20.48$57.25
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Price Card Drug Icon
Jublia1 bottle / 4ml of 10%
$791.07$1,012.44
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