Key takeaways
Naproxen (Naprosyn) and loratadine (Claritin) are both over-the-counter oral medications, but they belong to different drug classes and treat different conditions. Naproxen is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation from conditions like rheumatoid arthritis, osteoarthritis, and gout. It is also available by prescription and comes as a tablet and oral liquid. Loratadine, on the other hand, is an over-the-counter antihistamine used for allergy symptoms such as runny nose and watery eyes. It comes in a range of dosage forms, including capsule, tablet, orally disintegrating tablet, and oral liquid. While naproxen is typically taken 2 to 3 times a day, loratadine is usually taken once daily. Naproxen can cause side effects like heartburn, stomach pain, and nausea, and may interact with blood pressure medications. Loratadine is less likely to cause drowsiness compared to other antihistamines, but it can still cause headaches and tiredness.
