Key takeaways
Naproxen (Naprosyn) and Arthrotec (diclofenac/misoprostol) are both medications used to treat pain and inflammation, but they have some key differences. Naproxen is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking proteins that cause inflammation and pain. It is available in both prescription and over-the-counter forms. Arthrotec, on the other hand, is a combination of two medications: diclofenac, an NSAID, and misoprostol, a prostaglandin that protects the stomach from irritation caused by diclofenac. Arthrotec is specifically used for people with arthritis who are at high risk for stomach and intestinal ulcers. While both medications can cause serious side effects, Arthrotec is particularly dangerous for pregnant women. Naproxen is typically taken 2 times per day, whereas Arthrotec needs to be taken 2 to 4 times a day. Additionally, both medications are available as generics, making them potentially more affordable.
