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Mydayis vs. Dexedrine

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Mydayis (dextroamphetamine/amphetamine salts) and Zenzedi (dextroamphetamine) are both stimulant medications used to treat Attention Deficit Hyperactivity Disorder (ADHD), but they have some differences. Mydayis contains a mix of dextroamphetamine and amphetamine salts, while dextroamphetamine is a single-ingredient medication. Mydayis is available in an extended-release form that lasts up to 12 hours, whereas dextroamphetamine comes in both immediate-release and extended-release forms. Mydayis is typically taken once a day, while dextroamphetamine might need to be taken more frequently depending on the form. Mydayis is also available as a lower-cost generic, but some brands of dextroamphetamine, like Dexedrine Spansule, are only available as brand-name medications. Both medications have similar side effects, such as trouble sleeping and loss of appetite, and both carry risks of misuse and dependence. However, Mydayis is approved for use in children as young as six years old, while dextroamphetamine can be used in children as young as three years old.

Mydayis

 

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Dextroamphetamine

 

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Summary for Mydayis

Prescription only

Mydayis is a stimulant medication for attention deficit-hyperactivity disorder (ADHD). It contains an extended-release amphetamine salt combo (dextroamphetamine and amphetamine salts). Mydayis comes as a capsule for people 13 years of age and older. It's taken by mouth once a day in the morning after waking up. The dosage can be adjusted based on how well the medication works for you. Common side effects include low appetite, trouble sleeping, and dry mouth. It's a controlled substance because of its risk of misuse and dependency. Mydayis is a brand-name and generic medication.

Indications for Mydayis

Pros and Cons for Mydayis

Pros

  • A first-choice medication for ADHD
  • Taken by mouth once a day with or without food
  • Starts to work within 45 minutes and can last for up to 16 hours
  • Can open capsule and sprinkle contents on applesauce if you have trouble swallowing pills whole

Cons

  • Has a risk of misuse and dependency
  • A controlled medication, so there are special requirements for getting the prescription filled
  • Need to take gradually lower doses before stopping to prevent withdrawal symptoms
  • Not the best choice for people with heart conditions

Common Side Effects for Mydayis

Children:

  • Low appetite (22%)

Adults:

  • Trouble sleeping (31%)
  • Low appetite (30%)
  • Dry mouth (23%)

Warnings for Mydayis

  • Risk of misuse and addiction
  • Risks to people with serious heart conditions
  • Higher blood pressure and faster heart rate
  • Strange thoughts or behaviors
  • Slow growth in children
  • Problems with blood flow in the arms and legs, including Raynaud's phenomenon
  • Seizures
  • Serotonin syndrome

Summary for Dexedrine

Prescription only

Dextroamphetamine is used for the treatment of attention deficit-hyperactivity disorder (ADHD). It can also be used to treat uncontrollable daytime sleepiness (narcolepsy). Some side effects of the medication include difficulty sleeping, restlessness, and loss of appetite (that might lead to possible weight loss).

Indications for Dexedrine

  • Attention deficit-hyperactivity disorder (ADHD)
  • Narcolepsy (extreme daytime sleepiness)

Pros and Cons for Dexedrine

Pros

  • Available as a lower-cost generic medication
  • Available in immediate-release tablets and extended-release capsules
  • Available as a liquid solution if you have difficulty swallowing pills
  • Tablets and solution are okay to use in children as young as 3 years old

Cons

  • Has a risk of misuse and dependency
  • A controlled medication, so there are special requirements for getting the prescription filled
  • Can cause trouble sleeping if taken late in the day
  • Not the best option if you have heart problems

Common Side Effects for Dexedrine

  • Fast heartbeat
  • Loss of appetite
  • Stomach upset
  • Dry mouth
  • Dizziness
  • Headache
  • Tremors
  • Trouble sleeping

Warnings for Dexedrine

  • Misuse and dependence
  • Serious heart-related problems
  • Aggressive behavior and psychosis
  • Slowed growth in children
  • Seizures
  • Blood circulation problems (such as Raynaud's phenomenon)
  • Serotonin syndrome
  • Interactions with other medications

Prices with our coupons for Mydayis vs. Dexedrine

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Amphetamine Salt Combo XR (Mydayis)30 capsules / 50mg
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Dextroamphetamine60 tablets / 10mg
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