Key takeaways
Ibuprofen (Advil, Motrin) and naproxen (Naprosyn) are both nonsteroidal anti-inflammatory drugs (NSAIDs) used to relieve pain and inflammation. One key difference is that ibuprofen is available both over-the-counter and by prescription, while Naprosyn is only available by prescription (although a lower dose is available as a generic called Aleve). Ibuprofen is typically taken every 4 to 6 hours, whereas Naprosyn is taken less frequently, every 8 to 12 hours, which might be more convenient for some people. Both medications can cause side effects like stomach pain, heartburn, and nausea, but naproxen is more likely to cause drowsiness. Additionally, both medications can raise blood pressure and have risks of stomach bleeding, heart attack, and stroke, especially if taken for a long time or in higher doses. It's important to take these medications with food or milk to help prevent stomach issues and to avoid taking them together or with other NSAIDs. Always consult a healthcare professional to determine which medication is best for you.
