Key takeaways
Lovastatin (generic name: lovastatin) and Simvastatin (generic name: simvastatin) are both statins used to lower cholesterol and reduce the risk of heart attack and stroke. However, there are some differences between the two. Lovastatin is a low-to-moderate intensity statin and is typically taken once or twice a day with food, while Simvastatin is also a low-to-moderate intensity statin but is usually taken once daily in the evening. Simvastatin has a higher risk of causing severe muscle damage (rhabdomyolysis) compared to Lovastatin. Additionally, Simvastatin is available as an oral solution (Flolipid) for those who have trouble swallowing tablets, whereas Lovastatin does not have this option. Both medications should not be used during pregnancy or breastfeeding, and you should avoid grapefruit and grapefruit juice while taking either medication. Lastly, common side effects like headache and stomach pain are possible with both Simvastatin and Lovastatin.
