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MetroGel-Vaginal vs. Soolantra

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Metrogel (metronidazole) and Soolantra (ivermectin) are both topical treatments for rosacea, but they have some key differences. Metrogel is a nitroimidazole antibiotic that helps reduce redness and swelling by lowering inflammation. It is available in various forms, including gel, lotion, and cream, and is typically applied once a day. Soolantra, on the other hand, is an antiparasitic cream that also reduces inflammation and swelling, but its exact mechanism for treating rosacea is not fully understood. Experts believe it works by killing mites that live in the pores of people with rosacea. While both medications are available as a generic product, Soolantra can be expensive even though a generic version exists. Both medications can take several weeks to show significant improvement, but Soolantra may take up to three months for full results.

Metrogel

(metronidazole)

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Ivermectin cream

(Soolantra)

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Summary for MetroGel-Vaginal

Prescription only

Metrogel (metronidazole) is used on the skin to treat a certain skin disorder known as rosacea, a type of adult acne. It may help to decrease redness, swelling and the number of pimples caused by rosacea.

Indications for MetroGel-Vaginal

  • Adult acne

Pros and Cons for MetroGel-Vaginal

Pros

  • Works well to lower the swelling due to adult acne.
  • It has fewer side effects than oral tablets.
  • It is available as a generic product.
  • There are different strengths of Metrogel (metronidazole) available.
  • Available as a gel, lotion and cream.
  • Can still wear make-up under Metrogel (metronidazole).
  • Can be used in elderly people.

Cons

  • Can cause stinging, dryness, or irritation when applied.
  • It takes about 3-4 weeks to see significant improvement while using this medication.
  • Has to be used daily to see benefits from this medication.
  • Safety has not be studied in children.

Common Side Effects for MetroGel-Vaginal

  • Nasopharyngitis - a common cold that affects the nose and throat (3%)
  • Upper respiratory tract infection - a cold that affects the nose, throat, and lungs (3%)
  • Headache (2%)

Source: DailyMed

Warnings for MetroGel-Vaginal

  • EYE IRRITATION
  • WEAKNESS AND TINGLING SENSATION IN THE HANDS AND FEET
  • SKIN RASH

Summary for Soolantra

Prescription only

Ivermectin cream (Soolantra) works well for treating rosacea in adults. You apply the topical cream onto the affected areas of the face once a day. Ivermectin cream (Soolantra) is an antiparasitic medication, but it's not clear how it works to help with rosacea. Side effects aren't common but can include skin burning and irritation at the application site.

Indications for Soolantra

Pros and Cons for Soolantra

Pros

Cons

  • Can take a few months to see the full effects
  • Not clear whether the medication is safe for children or for people who are pregnant

Common Side Effects for Soolantra

See Risks and Warnings.

Warnings for Soolantra

  • Rash

Prices with our coupons for MetroGel-Vaginal vs. Soolantra

Price Card Drug Icon
Metronidazole1 tube / 45g of 0.75%
$26.98$153.39
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Price Card Drug Icon
Ivermectin1 tube / 45g of 1%
$100.97$101.42
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