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Compare Soolantra vs. Plexion

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Soolantra (ivermectin) and Avar (sulfacetamide/sulfur) are both topical medications used to treat rosacea, but they have some key differences. Soolantra is an antiparasitic cream that works by reducing inflammation and possibly killing mites in the pores, while Avar is a combination of an antibiotic (sulfacetamide) and sulfur, which stops bacteria from growing and helps renew the skin. Soolantra is applied once daily, whereas Avar can be used once or twice a day depending on the formulation. Avar is also used to treat acne and seborrheic dermatitis, making it more versatile than Soolantra, which is only for rosacea. Soolantra is known to be expensive without insurance, even though a generic is available, while Avar is available as a lower-cost generic. Both medications can cause skin irritation, but Avar has a higher risk of severe allergic reactions, especially if you have a sulfa allergy.

  • Ivermectin cream (Soolantra)
    Sulfacetamide / sulfur
  • Ivermectin cream (Soolantra)
    Sulfacetamide / sulfur

  • Summary of Soolantra vs. Plexion

    Summary for Antiparasitic
    Prescription only

    Ivermectin cream (Soolantra) works well for treating rosacea in adults. You apply the topical cream onto the affected areas of the face once a day. Ivermectin cream (Soolantra) is an antiparasitic medication, but it's not clear how it works to help with rosacea. Side effects aren't common but can include skin burning and irritation at the application site.

    Summary for Sulfonamide / keratolytic agent
    Prescription only

    Sulfacetamide / sulfur is a prescription topical skin product that's used to treat acne, rosacea, and seborrheic dermatitis. It's available as a generic medication as well as under many brand names, including Plexion, Avar, and Clenia Plus. It comes in different dosage forms, such as a cleanser, cream, lotion, face wash, and cloth. The medication is usually applied 1-3 times a day, and can be used by people 12 years and older. Side effects aren't common, but can include skin irritation in the area where it's applied.

  • Indications of Soolantra vs. Plexion

    Indications for
    •Rosacea
    Indications for
    •Acne
    •Rosacea
    •Seborrheic dermatitis

  • Pros and Cons of Soolantra vs. Plexion

    Pros and Const for Antiparasitic
    Pros
    •A recommended treatment option for rosacea
    •Only need to use once a day
    •Rarely causes side effects
    Cons
    •Can take a few months to see the full effects
    •Not clear whether the medication is safe for children or for people who are pregnant
    Pros and Const for Sulfonamide / keratolytic agent
    Pros
    •Applied directly to the affected area(s) on the skin
    •Available in many different formulations, such as lotion, cream, cleanser, cloths, and foam
    •Available as a lower-cost, generic medication
    Cons
    •Might need to apply multiple times per day
    •Not be the best option if you're allergic to sulfa medications
    •Not FDA approved for children under the age of 12 years old

  • Common Side Effects of Soolantra vs. Plexion

    Common Side Effects for

    See Risks and Warnings.

    Common Side Effects for

    See Risks and Warnings

  • Warnings of Soolantra vs. Plexion

    Common Side Effects for
    •Rash
    Common Side Effects for
    •Severe allergic reaction

  • Prices with our coupons for Soolantra vs. Plexion

    Learn more about Ivermectin cream
    Learn more about Sulfacetamide / sulfur

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