Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Sivextro (tedizolid) and Vancocin (vancomycin) are both antibiotics, but they treat different types of infections and belong to different drug classes. Sivextro (tedizolid) is an oxazolidinone antibiotic used to treat certain skin infections and is taken once daily for 6 days. It is available only as a brand-name medication. On the other hand, Vancocin (vancomycin) is a glycopeptide antibiotic used to treat *Clostridioides difficile* (C. diff) diarrhea and severe gut infections. It is taken 3 to 4 times a day for 7 to 10 days and is available in both brand-name and lower-cost generic forms. Sivextro (tedizolid) is less likely to cause gut-related side effects compared to linezolid (Zyvox), a similar medication, while Vancocin (vancomycin) can raise the risk of kidney damage and hearing problems. Additionally, Sivextro (tedizolid) is not well-studied for use during pregnancy and breastfeeding, whereas Vancocin (vancomycin) has specific warnings about potential kidney and hearing issues, especially in older adults.
Sivextro (tedizolid)
Vancomycin (Vancocin)
Sivextro (tedizolid)
Vancomycin (Vancocin)
Summary of Sivextro vs. Vancocin
Summary for Oxazolidinone antibiotic
Prescription only
Sivextro (tedizolid) is an antibiotic used to treat skin infections, such as cellulitis. It's taken once daily for 6 days. Sivextro (tedizolid) is available only as a brand-name medication in tablet and intravenous (IV) forms. Some common effects of this medication include nausea, diarrhea, and vomiting.
Summary for Glycopeptide
Prescription only
Vancomycin (Vancocin) is an antibiotic medication that's used to treat Clostridioides difficile (C. diff) diarrhea and certain severe gut infections in both adults and children. Vancomycin (Vancocin) is taken by mouth, typically 3 to 4 times a day. It's available as both oral capsules and a liquid. Common side effects of vancomycin (Vancocin) include nausea and stomach pain.
Indications of Sivextro vs. Vancocin
Indications for
•Certain skin infections in adults and children ages 12 years and older
Indications for
•Infectious diarrhea caused by Clostridioides difficile (C. diff)
•Gut inflammation (enterocolitis) caused by Staphylococcus aureus (S. aureus)