Key takeaways
Sivextro (tedizolid) and Cubicin (daptomycin) are both antibiotics used to treat skin infections, but they have some key differences. Sivextro (tedizolid) is an oxazolidinone antibiotic available only as a brand-name medication and can be taken orally or through an IV. It's typically taken once daily for 6 days. On the other hand, Cubicin (daptomycin) is a cyclic lipopeptide antibiotic that treats not only skin infections but also serious bloodstream infections. It's given as an IV injection, with the dosage and treatment length varying based on factors like age and kidney function. While Sivextro (tedizolid) is not recommended for children under 12, Cubicin (daptomycin) can be used in children as young as 1 year old. Additionally, Cubicin (daptomycin) is effective against MRSA and some other resistant bacteria, whereas Sivextro (tedizolid) is primarily used for skin infections. Both medications can cause diarrhea, but Cubicin (daptomycin) has a higher risk of severe muscle problems and kidney damage.
