Vancomycin (Vancocin) is an antibiotic medication that's used to treat Clostridioides difficile (C. diff) diarrhea and certain severe gut infections in both adults and children. Vancomycin (Vancocin) is taken by mouth, typically 3 to 4 times a day. It's available as both oral capsules and a liquid. Common side effects of vancomycin (Vancocin) include nausea and stomach pain.
Infectious diarrhea caused by Clostridioides difficile (C. diff)
Gut inflammation (enterocolitis) caused by Staphylococcus aureus (S. aureus)
Vancomycin (Vancocin) is a glycopeptide antibiotic. It kills bacteria by preventing them from making their own protective covering.
Source: DailyMed
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
Available in a liquid form (Firvanq) for people who have difficulty swallowing pills
First-line of treatment for C. diff diarrhea
Both oral capsules and solutions are available as lower-cost generic medications
Needs to be taken multiple times a day
Can raise the risk of kidney damage
Can cause nausea as a side effect
Be aware that if you're taking vancomycin (Vancocin) for C. diff diarrhea, your provider might decide to admit you to the hospital to prevent the spread of C. diff during treatment. Make sure to follow your provider's instructions to lower the risk of passing on the infection to someone else.
Take vancomycin (Vancocin) exactly as prescribed. Make sure to finish your treatment course, even if you're feeling better. Stopping the medication earlier than prescribed can make your infection come back and become harder to treat.
If you're using vancomycin (Vancocin) for C. diff diarrhea, let your provider know if your diarrhea gets worse after you start taking it. You might need a different medication.
Let your provider know if you experience hearing loss or difficulty maintaining your balance after you start vancomycin (Vancocin). Though not common, this medication can affect your hearing and balance.
Vancomycin (Vancocin) can sometimes cause serious skin reactions. Watch out for symptoms such as skin rash or blisters. Stop this medication and get medical attention right away if these reactions happen.
Tips for vancomycin (Vancocin) oral suspension
Shake the bottle well before using. Make sure to only use a medication dose cup or syringe from the pharmacy to measure out your dose. Don't use household spoons because they aren't accurate and might cause you to take the wrong dose.
Store vancomycin (Vancocin) liquid in the refrigerator for up to 14 days. Then, throw away the bottle, even if there's still some medication left. Don't take and throw away the medication if it looks cloudy or has particles.
Vancomycin (Vancocin) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Risk factors: Inflamed intestines | Taking an aminoglycoside antibiotic at the same time | Current kidney problems
If you're taking vancomycin (Vancocin) by mouth, it's possible for some of the medication to be absorbed into your bloodstream and cause more side effects. The risk is higher if you've inflammation in your intestines, kidney problems, or are taking an aminoglycoside antibiotic at the same time. If you've any of these risk factors, let your provider know before starting treatment with vancomycin (Vancocin). Your provider might order blood tests to make sure this medication is safe for you.
Risk factors: History of kidney problems | Taking other medications that can cause kidney problems | Age 65 years and older
Though not common, vancomycin (Vancocin) can cause serious kidney problems. The risk is higher for certain people, such as older adults. Your provider might order blood work during during and after your treatment with vancomycin (Vancocin) to check your kidney health. Let your provider know right away if you have possible symptoms of kidney problems, such as feeling tired or seeing swelling in your hands and feet.
Risk factors: Older adults | History of hearing problems | Taking other medications that can cause hearing problems | Receiving vancomycin injection
Rarely, people who take vancomycin (Vancocin) can sometimes experience hearing problems that can be temporary or permanent. These side effects are more common in people receiving vancomycin injections or taking other medications that cause hearing problems. Your provider might order hearing tests before and during vancomycin (Vancocin) treatment to make sure this medication is safe for you. If you experience difficulty hearing, ringing in the ears, or a spinning sensation, please talk with your provider right away because you might need to stop this medication.
Vancomycin (Vancocin) can sometimes cause rash and other severe skin reactions, such as drug reaction with eosinophilia and systemic symptoms (DRESS) and Stevens-Johnson syndrome (SJS). If you experience these reactions, your provider will need to stop vancomycin (Vancocin) right away and switch you to a different medication. If you have a rash, blisters on your lips, skin peeling, skin pain, mouth sores, or high fever, get medical help immediately.
Risk factors: Allergy to tartrazine | Aspirin allergy
Certain vancomycin (Vancocin) tablets contain a dye called FD&C Yellow No. 5 (tartrazine). If you're allergic to tartrazine, let your provider know right away. They can help you choose a manufacturer that doesn't use this dye. Get medical help right away if you experience trouble breathing after taking vancomycin (Vancocin) because you might be having an allergic reaction.
Adults
Infectious diarrhea: The typical dose is 125 mg by mouth 4 times daily for 10 days.
Inflamed gut: The typical dose is 500 mg to 2 grams by mouth daily, split into 3 or 4 doses and taken throughout the day for 7 to 10 days.
Children
Infectious diarrhea and inflamed gut: Your child's provider will determine your child's dose based on their body weight. The typical dose is 40 mg/kg of body weight by mouth daily, split into 3 or 4 doses and taken throughout the day for 7 to 10 days. The maximum recommended dose is 2 grams daily.
Infectious diarrhea caused by Clostridioides difficile (C. diff)
Gut inflammation (enterocolitis) caused by Staphylococcus aureus (S. aureus)
Clostridioides difficile (C. diff) diarrhea in people ages 6 months and older
Amebiasis (parasitic gut infection)
Serious bacterial infections, such as:
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Azurity Pharmaceuticals, Inc. (2023). Firvanq- vancomycin hydrochloride kit [package insert]. DailyMed.
McDonald, L. C., et al. (2018). Clinical practice guidelines for Clostridium difficile infection in adults and children: 2017 update by SHEA/IDSA. Clinical Infectious Diseases.
National Kidney Foundation. (2020). 10 signs you may have kidney disease.
Oman Evans II, M., et al. (2016). Tea and recurrent Clostridium difficile infection. Gastroenterology Research and Practice.
PAI Holdings, LLC. (2023). Vancomycin hydrochloride capsule [package insert]. DailyMed.
Patel, S., et al. (2023). Vancomycin. StatPearls.
Wilshire Pharmaceuticals, Inc. (2023). Vancomycin hydrochloride for oral solution- vancomycin hydrochloride [package insert]. DailyMed.
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