Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Azelaic acid (Finacea) and clindamycin (Clindesse) are both prescription medications used to treat skin conditions, but they belong to different medication classes and have distinct uses. Azelaic acid is a dicarboxylic acid used topically to treat mild-to-moderate rosacea, while clindamycin is a lincosamide antibiotic used vaginally to treat bacterial infections like bacterial vaginosis. Azelaic acid is available as a gel and foam, applied twice daily, and has a generic version available, making it more affordable. In contrast, clindamycin comes as a cream and gel, with some formulations requiring only a single dose, but only Cleocin has a generic version. Azelaic acid can cause skin irritation, such as burning and dryness, and may lighten skin color, while clindamycin can lead to yeast infections and weaken condoms and diaphragms. Additionally, clindamycin can cause severe diarrhea, especially in those with a history of bowel problems. Both medications require careful use to avoid side effects and interactions with other products.
Azelaic acid (Finacea)
Clindamycin vaginal cream
Azelaic acid (Finacea)
Clindamycin vaginal cream
Summary of Finacea vs. Clindesse
Summary for Dicarboxylic acid
Prescription only
Azelaic acid (Finacea) is a dicarboxylic acid. It's a topical medication used to treat mild-to-moderate rosacea in adults. It works by easing skin redness and inflammation. Azelaic acid (Finacea) is applied to the skin twice daily, in the morning and evening. This medication comes as a gel and foam. Some side effects of azelaic acid (Finacea) include mild burning, tingling, and itching. It's available as brand name and generic medications.
Summary for Lincosamide antibiotic
Prescription only
Clindamycin vaginal cream is an antibiotic used to treat bacterial vaginosis (BV). It’s available under two brand names, Clindesse and Cleocin, and applied inside the vagina using an applicator. Clindesse is a single-dose treatment used one time, while Cleocin and its generic versions are typically used once a day at bedtime for 3 or 7 days. Common side effects include vaginal irritation and yeast infections.
Indications of Finacea vs. Clindesse
Indications for
•Treatment of papules and pustules in adults with mild-to-moderate rosacea