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MetroGel-Vaginal vs. Plexion

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Metrogel (metronidazole) and Avar (sulfacetamide/sulfur) are both topical treatments used for skin conditions, but they have some key differences. Metrogel (metronidazole) is primarily used to treat rosacea, reducing redness and swelling, and is available in gel, lotion, and cream forms. It typically needs to be applied once a day and can take 3 to 4 weeks to show significant improvement. On the other hand, Avar (sulfacetamide/sulfur) is a combination medication used for acne, rosacea, and seborrheic dermatitis. It combines an antibiotic (sulfacetamide) and sulfur, which helps shed old skin. Avar can be applied once or twice daily and may take up to 12 weeks to see effects. While Metrogel is known for fewer side effects and can be used with makeup, Avar may have an offensive odor and can stain clothing. Additionally, Avar is not suitable for those with sulfa allergies and may not be appropriate during pregnancy or for children under 12.

Metrogel

(metronidazole)

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sulfacetamide / sulfur

 

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Summary for MetroGel-Vaginal

Prescription only

Metrogel (metronidazole) is used on the skin to treat a certain skin disorder known as rosacea, a type of adult acne. It may help to decrease redness, swelling and the number of pimples caused by rosacea.

Indications for MetroGel-Vaginal

  • Adult acne

Pros and Cons for MetroGel-Vaginal

Pros

  • Works well to lower the swelling due to adult acne.
  • It has fewer side effects than oral tablets.
  • It is available as a generic product.
  • There are different strengths of Metrogel (metronidazole) available.
  • Available as a gel, lotion and cream.
  • Can still wear make-up under Metrogel (metronidazole).
  • Can be used in elderly people.

Cons

  • Can cause stinging, dryness, or irritation when applied.
  • It takes about 3-4 weeks to see significant improvement while using this medication.
  • Has to be used daily to see benefits from this medication.
  • Safety has not be studied in children.

Common Side Effects for MetroGel-Vaginal

  • Nasopharyngitis - a common cold that affects the nose and throat (3%)
  • Upper respiratory tract infection - a cold that affects the nose, throat, and lungs (3%)
  • Headache (2%)

Source: DailyMed

Warnings for MetroGel-Vaginal

  • EYE IRRITATION
  • WEAKNESS AND TINGLING SENSATION IN THE HANDS AND FEET
  • SKIN RASH

Summary for Plexion

Prescription only

Sulfacetamide / sulfur is a prescription topical skin product that's used to treat acne, rosacea, and seborrheic dermatitis. It's available as a generic medication as well as under many brand names, including Plexion, Avar, and Clenia Plus. It comes in different dosage forms, such as a cleanser, cream, lotion, face wash, and cloth. The medication is usually applied 1-3 times a day, and can be used by people 12 years and older. Side effects aren't common, but can include skin irritation in the area where it's applied.

Indications for Plexion

Pros and Cons for Plexion

Pros

  • Applied directly to the affected area(s) on the skin
  • Available in many different formulations, such as lotion, cream, cleanser, cloths, and foam
  • Available as a lower-cost, generic medication

Cons

  • Might need to apply multiple times per day
  • Not be the best option if you're allergic to sulfa medications
  • Not FDA approved for children under the age of 12 years old

Common Side Effects for Plexion

See Risks and Warnings

Warnings for Plexion

  • Severe allergic reaction

Prices with our coupons for MetroGel-Vaginal vs. Plexion

Price Card Drug Icon
Metronidazole1 tube / 45g of 0.75%
$26.98$153.39
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Price Card Drug Icon
Sulfacetamide/Sulfur1 bottle / 8 oz of 10%/5%
$21.63$378.98
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