Key takeaways
Metformin (Glumetza, Riomet) and semaglutide (Wegovy) are both medications that can manage metabolic conditions like diabetes or obesity. Metformin is a biguanide that treats Type 2 diabetes, helping control blood sugar by reducing the amount of sugar your body makes and improving insulin use in the body. It is taken orally, usually once or twice a day, and is available in both short-acting and long-acting forms. Common side effects include stomach issues like diarrhea and nausea. Semaglutide, on the other hand, is a glucagon-like peptide-1 (GLP-1) receptor agonist that is injected under the skin once a week. As Wegovy, it is primarily used for long-term weight management and to lower the risk of heart problems in certain adults. Other forms of semaglutide like Ozempic and Rybelsus are used for treating Type 2 diabetes. Common side effects include nausea, diarrhea, and stomach pain. Unlike metformin, semaglutide injection requires refrigeration and has a potential risk for thyroid cancer. Both medications can interact with other diabetes medications, potentially causing low blood sugar.
