Key takeaways
Meloxicam (Mobic) and nabumetone (Relafen) are both prescription NSAIDs used to treat arthritis pain, but they have some differences. Meloxicam is available in multiple forms, including capsules, tablets, oral suspension, and injection, while nabumetone is only available as an oral tablet. Meloxicam tends to block COX-2 more than COX-1, which may result in fewer stomach and kidney side effects compared to other NSAIDs. Nabumetone, on the other hand, is a non-selective COX inhibitor. Both medications can raise the risk of serious side effects like stomach bleeding, heart attack, and kidney problems. Both medications also have potential to cause severe asthma attacks in some people. Additionally, neither is not recommended during late pregnancy, especially after 20 weeks. Both medications should be taken with caution if you have a history of heart, liver, or kidney problems.
