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Lodine vs. Warfarin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Etodolac

 

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Warfarin

(Coumadin)

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Summary for Lodine

Prescription only

Etodolac, also known by its brand name Lodine, is a non-steroidal anti-inflammatory drug (NSAID). The immediate-release pills are taken throughout the day; they're approved for adults with sudden, short-term pain; rheumatoid arthritis; or osteoarthritis. There's also an extended-release tablet for people ages 6 years and older that's taken once per day for the same types of arthritis. Side effects can include stomach pain, dizziness, and rash. Etodolac is currently available by prescription as generic only; the brand name has been discontinued.

Indications for Lodine

Pros and Cons for Lodine

Pros

  • Works well to treat pain and inflammation
  • Extended-release tablets can be used for children as young as 6 years old
  • Available as a lower-cost generic

Cons

  • Only available as pills that can't be split, open, or crushed
  • Not safe to take after 20 weeks of pregnancy
  • Might not be the best option if you're 65 years or older or if you have kidney, heart, liver, or bleeding problems

Common Side Effects for Lodine

The following side effects were reported in 1% to 10% of people who took etodolac:

Warnings for Lodine

  • Stomach bleeding
  • Heart attack and stroke
  • High blood pressure and heart failure
  • Kidney damage
  • Liver problems
  • Severe allergic reactions and skin reactions
  • Not safe to take while pregnant
  • Risk for bleeding

Summary for Warfarin

Prescription only

Warfarin (Coumadin) is a blood thinner (anticoagulant). It's used to prevent and treat blood clots in adults and children with conditions such as deep vein thrombosis (DVT) or pulmonary embolism (PE). Warfarin (Coumadin) is taken by mouth, typically once daily. Your provider will adjust the dose based on your international normalized ratio (INR). Taking too much warfarin (Coumadin) can lead to side effects like bruising and serious bleeding. If needed, your provider can give you an antidote to reverse the effects of warfarin (Coumadin).

Indications for Warfarin

  • Prevention and treatment blood clots in the veins
  • Prevention and treatment blood clots linked to atrial fibrillation (AFib) or heart valve replacement
  • Prevention of more blood clots and to lower risk of death after a heart attack

Pros and Cons for Warfarin

Pros

  • Each strength of tablet is a unique color, making it easy to tell them apart
  • Only needs to be taken once a day
  • Has an antidote available in case of an emergency
  • Available as a lower-cost generic

Cons

  • Only prevents new blood clots from forming or getting bigger; it doesn't work on existing blood clots
  • Requires regular blood draws to check INR levels
  • Interacts with foods and many commonly-prescribed medications
  • Not safe to take during pregnancy

Common Side Effects for Warfarin

  • Bleeding
  • Bruising

Warnings for Warfarin

  • Severe or life-threatening bleeding
  • Risk of blood clots from stopping too early
  • Risk of fat-containing clots
  • Calcium build-up in blood vessels (calciphylaxis)
  • Skin or tissue death and risk of gangrene
  • Not for use during pregnancy

Prices with our coupons for Lodine vs. Warfarin

Price Card Drug Icon
Etodolac60 tablets / 400mg
$25.84$78.76
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Price Card Drug Icon
Warfarin30 tablets / 5mg
$4.00$4.00
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