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Lisinopril vs. Betapace

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Lisinopril (Zestril) and sotalol (Betapace) are both prescription medications, but they serve different purposes and belong to different drug classes. Lisinopril is an ACE inhibitor used primarily to lower blood pressure, treat heart failure, and reduce the risk of death after a heart attack. It works by relaxing blood vessels. On the other hand, Sotalol is an antiarrhythmic medication used to treat and prevent certain types of heart rhythm problems, like atrial fibrillation. It works by blocking potassium channels and beta receptors in the heart to slow down electrical activity and heart rate. Lisinopril is typically taken once daily, while Sotalol is usually taken twice daily and requires initial monitoring in a hospital. Common side effects of Lisinopril include cough and dizziness, whereas Sotalol can cause tiredness, dizziness, and low heart rate. Both medications are available in generic forms, making them more affordable.

Lisinopril

(Zestril)

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Sotalol

(Betapace)

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Summary for Lisinopril

Prescription only

Lisinopril (Zestril) is an angiotensin-converting enzyme inhibitor, or ACE inhibitor. It's used to treat high blood pressure in people 6 years and older. In adults, it's also approved to manage heart failure and to lower the risk of death after a heart attack. Lisinopril (Zestril) comes as a tablet that's taken by mouth once daily. There's also an oral solution available under the brand name Qbrelis. Some side effects include dizziness, cough, and headache.

Indications for Lisinopril

Pros and Cons for Lisinopril

Pros

  • Taken by mouth once per day
  • A first-choice medication for high blood pressure
  • Also helpful for heart failure and after a heart attack
  • Okay for children as young as 6 years old to take to treat high blood pressure

Cons

Common Side Effects for Lisinopril

  • Dizziness (up to 19%)
  • Low blood pressure (up to 11%)
  • Higher creatinine levels (up to 10%)

Warnings for Lisinopril

  • Harm to an unborn baby
  • Angioedema (swelling)
  • Low blood pressure
  • Possible worsening of kidney problems
  • High potassium levels
  • Liver problems

Summary for Betapace

Prescription only

Sotalol (Betapace) is used to treat and prevent certain types of heart rate and heart rhythm problems (like atrial fibrillation or Afib). It's taken by mouth, typically twice a day. Usually, you need to start this medication in the hospital and stay there for at least 3 days so that the healthcare team can monitor your heart rhythm and check for any serious side effects. Sotalol (Betapace) can interact with several medications, including certain blood pressure medications and antacids. Sotalol is available both generic and brand name medications.

Indications for Betapace

Pros and Cons for Betapace

Pros

  • Works well to treat life-threatening arrhythmias
  • Available in a lower-cost, generic version
  • Available as an oral liquid for people having trouble swallowing tablets

Cons

  • Must in a hospital for 3 days when first starting
  • Can cause serious arrhythmias, so it requires close monitoring
  • Can't use in people with certain medical conditions (e.g., heart failure, severe kidney problems, breathing problems)

Common Side Effects for Betapace

  • Tiredness (up to 20%)
  • Dizziness (up to 16%)
  • Low heart rate (up to 13%)
  • Headache (up to 12%)
  • Trouble breathing (up to 10%)

Warnings for Betapace

  • Life-threatening abnormal heart rhythm
  • Low blood pressure and heart rate
  • Heart failure
  • Difficulty breathing (bronchospasm)
  • Masked symptoms of low blood sugar
  • Heart issues with sudden discontinuation
  • Severe allergic reactions

Prices with our coupons for Lisinopril vs. Betapace

Price Card Drug Icon
Lisinopril30 tablets / 20mg
$7.79$13.70
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Sotalol60 tablets / 80mg
$14.99$43.38
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