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Lidoderm vs. Menthol

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Lidoderm (lidocaine 5% patch) and topical menthol (BioFreeze, IcyHot) are both topical medications used to relieve pain, but they belong to different drug classes and have distinct uses. Lidoderm is a local anesthetic available by prescription and is specifically FDA-approved for treating nerve pain caused by shingles, known as postherpetic neuralgia. It works by numbing the nerves in the skin. In contrast, menthol is an over-the-counter topical analgesic used for minor aches and pains in muscles and joints, such as those from arthritis, backache, and strains. Lidoderm is applied as a 5% patch that you wear for up to 12 hours in a 24-hour period, while menthol comes in various forms like patches, gels, and sprays, with patches typically worn for up to 8 hours. Lidoderm can cause skin irritation and has potential interactions with other medications, while menthol is generally well-tolerated but can cause serious skin burns if misused. Additionally, Lidoderm patches can be cut to fit the area of pain, whereas menthol patches should not be cut.

Lidocaine 5% patch

(Lidoderm)

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Menthol

 

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Summary for Lidoderm

Prescription only

Lidocaine 5% patch (Lidoderm) is a prescription medication used to relieve nerve pain caused by a shingles infection, also called postherpetic neuralgia (PHN). It's a local anesthetic that works by numbing your nerves to help reduce pain. You apply the patch directly to the painful area of your skin once a day, and it can be worn for up to 12 hours in a 24-hour period. Common side effects include temporary skin irritation, redness, and a mild burning sensation where the patch is applied.

Indications for Lidoderm

Pros and Cons for Lidoderm

Pros

  • Works directly on the skin
  • Generally well-tolerated with few side effects
  • Can cut patches to fit the area of pain

Cons

  • Commonly causes skin irritation
  • Must avoid contact with water wearing the patch
  • Might interact with many medications

Common Side Effects for Lidoderm

  • Blisters
  • Bruising
  • Burning sensation
  • Changes in skin color
  • Rash or redness
  • Swelling
  • Peeling or flaking skin
  • Itching
  • Small bumps or spots
  • Tiny red or purple dots under the skin
  • Tingling or numbness in the area

Warnings for Lidoderm

  • Blood problem (methemoglobinemia)
  • Absorbing too much medication
  • Accidental poisoning in children or pets

Summary for Menthol

Over-the-counter

Menthol is a medication that's applied to the skin to help relieve minor aches and pains. It's available over the counter (OTC) as brand-name and lower-cost generic options. Menthol comes in many different forms including patches, gel, cream, spray, and topical liquid. This medication doesn't cause many side effects, but it might not work as well as some other pain relief formulations that contain multiple ingredients.

Indications for Menthol

Minor aches and pains in muscles and joints related to:

  • Arthritis
  • Backache
  • Strains
  • Sprains
  • Bruises
  • Cramps
  • Bursitis (inflamed bursa)
  • Tendonitis (inflamed tendon)

Pros and Cons for Menthol

Pros

  • Available OTC as a lower-cost generic
  • Comes in many different formulations
  • Can be applied directly to the painful area
  • Generally well tolerated with few side effects
  • Patches can be worn for up to 8 hours.

Cons

  • Can't apply to irritated or damaged skin
  • Shouldn't be used for more than 7 days at a time
  • Can cause irritation if it makes contact with the eyes
  • Shouldn't be used with other topical skin products
  • Patches won't stick well to damp or wet skin.

Common Side Effects for Menthol

  • Skin irritation

Warnings for Menthol

  • Risk of serious skin burns

Prices with our coupons for Lidoderm vs. Menthol

Price Card Drug Icon
Lidocaine30 patches / 5%
$60.46$288.87
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Menthol6 cartons / 5 patches of 5%
$19.61$39.04
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