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Lastacaft vs. Nedocromil

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Lastacaft (alcaftadine) and Alocril (nedocromil) are both eye drops used to treat allergy-related eye symptoms, such as itching and redness. They are similar in that they both help manage allergic conjunctivitis, but they have some important differences. Lastacaft is an antihistamine and mast cell stabilizer, while Alocril is only a mast cell stabilizer. Lastacaft is available over-the-counter and is typically used once daily, whereas Alocril requires a prescription and is used twice daily. Both medications are only available in a branded version. Common side effects of Lastacaft include eye irritation and burning, while Alocril can cause headaches, eye irritation, and an unpleasant taste in the mouth. If you wear soft contact lenses, remove them and do not put them back in for 10 minutes after using Lastacraft. Wearing contact lenses while using Alocril is not recommended.

Lastacaft

(alcaftadine)

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Alocril

(nedocromil)

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Summary for Lastacaft

Over-the-counter

Lastacaft (alcaftadine) is a once-daily anti-allergy eye drop. It was previously available only by prescription, but you can now get it over the counter.

Indications for Lastacaft

  • Eye itching or redness due to allergies (allergic conjunctivitis)

Pros and Cons for Lastacaft

Pros

  • Used just once daily
  • Can be given to children as young as 2 years of age
  • Doesn't leave weird aftertaste like the similar medication called Bepreve (bepotastine)

Cons

  • Can cause eye pain and irritation
  • Not for itching caused by infections or contact lenses
  • Can be more expensive than many alternatives

Common Side Effects for Lastacaft

  • Eye irritation
  • Burning and stinging in the eye
  • Eye redness
  • Eye itching

Warnings for Lastacaft

  • Contamination of dropper tip and solution
  • Contact lens use

Summary for Nedocromil

Prescription only

Alocril (nedocromil) is an eye drop for eye-related allergy symptoms, such as itchiness or watery eyes. Typically, you place 1 to 2 drops into your eyes twice daily. But it's not a first-choice option for allergy symptoms. Some common side effects of this medication include headaches and eye irritation.

Indications for Nedocromil

  • Itchy or watery eyes from allergy

Pros and Cons for Nedocromil

Pros

  • Relieves itchy and red eyes due to allergies
  • Can be combined with oral allergy medications
  • Can be used in children age 3 years and older

Cons

Common Side Effects for Nedocromil

  • Headache (40%)
  • Eye burning, stinging, or irritation (10-30%)
  • Unpleasant taste in the mouth (10-30%)
  • Stuffy nose (10-30%)

Warnings for Nedocromil

  • Contamination of dropper tip and solution
  • Avoid contact lenses

Prices with our coupons for Lastacaft vs. Nedocromil

Price Card Drug Icon
Lastacaft1 eye dropper / 3ml of 0.25%
$284.00$284.00
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Price Card Drug Icon
Alocril1 eye dropper / 5ml of 2%
$235.35$308.67
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