Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Terbinafine (Lamisil) and Jublia (efinaconazole) are both antifungal medications used to treat nail fungus, but they have some key differences. Terbinafine is taken orally as a tablet, while Jublia is a topical solution applied directly to the toenail. Terbinafine is typically taken once a day for 6 to 12 weeks, whereas Jublia is applied daily for about 11 months. Terbinafine can cause side effects like headache, rash, and upset stomach, and it has a risk of serious liver damage. Jublia, on the other hand, mainly causes local side effects like ingrown toenails and skin irritation. Terbinafine is available as a lower-cost generic, but Jublia does not have a generic version. Additionally, Jublia is only approved for toenail fungus, while terbinafine can treat both fingernail and toenail infections.
Terbinafine
jublia (efinaconazole)
Terbinafine
jublia (efinaconazole)
Summary of Lamisil vs. Jublia
Summary for Antifungal
Prescription only
Terbinafine is used to treat fingernail and toenail fungus in adults. It's a type of antifungal that helps get rid of the fungus. Terbinafine is a tablet you take once a day, but treatment can take many weeks to finish. Common side effects include headache, rash, and diarrhea. Terbinafine can interact with other medications, including certain antidepressants and beta blockers.
Summary for Antifungal
Prescription only
Jublia (efinaconazole) is a prescription antifungal medication used to treat toenail fungus in people 6 years and older. It comes as a topical solution that you apply once a day directly to the affected toenail and the skin around it. Treatment usually lasts for almost a year. Common side effects include ingrown toenail and redness, itching, or irritation at the application site.