Key takeaways
Lactulose (Constulose) and polyethylene glycol 3350 (Miralax) are both osmotic laxatives used to treat constipation, but they have some key differences. Lactulose is a prescription medication, while Miralax is available over-the-counter. Lactulose typically takes 1 to 2 days to work, whereas Miralax can take 1 to 3 days. Lactulose can cause side effects like stomach pain and gas, and it might not be suitable for people who are lactose intolerant or on a low-galactose diet. On the other hand, Miralax is less likely to cause these side effects and is considered safer for people with kidney problems. Additionally, Miralax is tasteless and can be mixed with various beverages, making it easier to take. If you need quick relief from constipation, neither medication may be the best option since they can several days to work.
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