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Geodon vs. Zyprexa

Ziprasidone (Geodon) is an atypical antipsychotic medication used to treat bipolar I disorder and schizophrenia in adults. It works by balancing the levels of certain chemicals in the brain, like dopamine and serotonin. Ziprasidone (Geodon) is taken by mouth, typically twice daily. It's also available as an injection that's given into the muscles by a healthcare provider to treat agitation in schizophrenia. Some common side effects of ziprasidone (Geodon) include uncontrolled body movements, sleepiness, and nausea.

• Bipolar I disorder
• Schizophrenia

• Uncontrolled body movements (14%)
• Sleepiness (14%)
• Nausea (10%)
• Constipation (9%)
• Indigestion (8%)
• Restlessness (8%)
• Dizziness (8%)
• Respiratory tract infection (8%)

Note: Side effects listed were reported by people who took ziprasidone for schizophrenia in a clinical study

• Higher risk of death in older adults with dementia-related psychosis
• Risk of suicidal thoughts and behavior
• Difficulty controlling muscle movements (tardive dyskinesia)
• Weight gain, higher blood sugar, and higher cholesterol levels
• Neuroleptic malignant syndrome
• Difficulty concentrating and extreme sleepiness
• Changes in blood pressure and higher risk of falls
• Risk of infection (from low white blood cell count)
• Seizures
• Serious skin reaction
• Prolonged and painful erection
• High prolactin levels
• Heart rhythm problems

Olanzapine (Zyprexa) is an atypical antipsychotic used treat schizophrenia or bipolar disorder. It can also treat depression, in combination with fluoxetine (Prozac), when other treatments haven't worked well. This medication is thought to work by balancing the levels of certain chemicals in the brain. Olanzapine (Zyprexa) is taken by mouth, typically once daily, by adults and children. Olanzapine (Zyprexa) is also available as an injection that's usually given in a hospital or clinic setting. Some of the more common side effects of olanzapine (Zyprexa) include sleep problems, dizziness, and weight gain.

• Schizophrenia in adults and children age 13 years and older
• Bipolar I disorder in adults and children age 13 years and older

When taken with fluoxetine (Prozac):

• Bipolar depression in adults and children age 10 years and older
• Depression that hasn't responded well to other treatments

• Sleepiness (29%)
• Trouble sleeping (12%)
• Accidental injury (12%)
• Dizziness (11%)
• Weakness (10%)
• Dry mouth (9%)
• Constipation (9%)
• Upset stomach (7%)
• Runny nose (7%)

• Higher risk of death in older people with dementia-related psychosis
• Worsening depression, suicidal thoughts and behavior
• Severe allergic skin reactions
• Neuroleptic malignant syndrome
• Weight gain, higher blood sugar, and higher cholesterol levels
• Difficulty controlling body movements
• Changes in blood pressure and higher risk of falls
• Risk of infection (from low white blood cell count)
• Seizures
• High prolactin levels
• Difficulty concentrating and extreme sleepiness
• Anticholinergic side effects