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Geodon vs. Invega

Ziprasidone (Geodon) is an atypical antipsychotic medication used to treat bipolar I disorder and schizophrenia in adults. It works by balancing the levels of certain chemicals in the brain, like dopamine and serotonin. Ziprasidone (Geodon) is taken by mouth, typically twice daily. It's also available as an injection that's given into the muscles by a healthcare provider to treat agitation in schizophrenia. Some common side effects of ziprasidone (Geodon) include uncontrolled body movements, sleepiness, and nausea.

• Bipolar I disorder
• Schizophrenia

• Uncontrolled body movements (14%)
• Sleepiness (14%)
• Nausea (10%)
• Constipation (9%)
• Indigestion (8%)
• Restlessness (8%)
• Dizziness (8%)
• Respiratory tract infection (8%)

Note: Side effects listed were reported by people who took ziprasidone for schizophrenia in a clinical study

• Higher risk of death in older adults with dementia-related psychosis
• Risk of suicidal thoughts and behavior
• Difficulty controlling muscle movements (tardive dyskinesia)
• Weight gain, higher blood sugar, and higher cholesterol levels
• Neuroleptic malignant syndrome
• Difficulty concentrating and extreme sleepiness
• Changes in blood pressure and higher risk of falls
• Risk of infection (from low white blood cell count)
• Seizures
• Serious skin reaction
• Prolonged and painful erection
• High prolactin levels
• Heart rhythm problems

Invega (paliperidone) is taken by mouth and used to improve mood, thoughts, and behaviors in people who have schizophrenia or schizoaffective disorder. It's available as both brand and generic versions in an extended-release pill, which means the medication is released slowly in your body. It only needs to be taken once a day. Some common side effects include drowsiness and uncontrolled muscle movements. There are long-acting injection forms of this medication available given by a trained healthcare provider.

• Schizophrenia
• Schizoaffective disorder

• Abnormal muscle movements (up to 40%)
• Drowsiness (up to 26%)
• Headache (up to 14%)
• Irregular heart beat (up to 14%)
• Vomiting (up to 11%)
• Anxiety (up to 9%)

• Higher risk of death in older adults with dementia-related psychosis
• Neuroleptic malignant syndrome (NMS)
• High blood sugar, high cholesterol, and weight gain
• Difficulty controlling muscle movements (tardive dyskinesia)
• Higher risk of falls
• High prolactin levels
• Higher risk of infections
• Not for people with gut problems
• Heart rhythm problem (QT prolongation)