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Gentamicin vs. Flagyl

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Gentak (gentamicin) and Flagyl (metronidazole) are both antibiotics, but they treat different types of infections and are used in different ways. Gentak (gentamicin) is an aminoglycoside antibiotic used as eye drops or ointment to treat bacterial infections of the eye or eyelid, such as pink eye or blepharitis. It works by blocking bacteria from making proteins they need to survive. On the other hand, Flagyl (metronidazole) is a nitroimidazole antibiotic taken by mouth to treat various bacterial and parasitic infections, including trichomoniasis and bacterial vaginosis. It kills bacteria and parasites by damaging their genetic material. While Gentak is applied directly to the eye and starts working right away, Flagyl is taken orally and can cause side effects like nausea and a metallic taste. Additionally, you must avoid alcohol while taking Flagyl and for three days after, as it can cause a serious reaction. Both medications are available in lower-cost generic forms and require a prescription.

Gentamicin

 

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Metronidazole

(Flagyl)

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Summary for Gentamicin

Prescription only

Gentamicin is a topical antibiotic that treats bacterial skin infections, such as impetigo. It comes as a cream that's useful for wet, oozing, or greasy skin infections. There's also a topical ointment for infections on dry skin. Both forms are applied on the skin 3 to 4 times a day. Gentamicin can be used on adults and children over 1 year of age. Most people don't have many side effects when used as directed. But it's possible to have mild skin irritation, like redness and itching.

Indications for Gentamicin

  • Impetigo
  • Other bacterial skin infections

Pros and Cons for Gentamicin

Pros

  • Treats various bacterial skin infections, including severe acne or impetigo
  • Very few side effects, so it's safe for most people if used as directed
  • Might be a good option for people who are sensitive to Neosporin

Cons

  • Applied many times a day
  • Can cause temporary skin irritation
  • Need a prescription from a healthcare professional

Common Side Effects for Gentamicin

  • Side effects aren't common. See "Other Side Effects."

Warnings for Gentamicin

  • Risk of other skin infections
  • Allergic reaction

Summary for Flagyl

Prescription only

Metronidazole (Flagyl) is an oral antibiotic for adults and children. It's used to treat certain bacterial and parasitic infections, including bacterial vaginosis (a type of vaginal bacteria infection) and trichomoniasis (a sexually transmitted infection, or STI). Metronidazole (Flagyl) is taken by mouth, typically 3 times a day. Some common side effects of this medication include diarrhea, nausea, and vomiting. Avoid drinking alcohol while taking and for 3 days after stopping metronidazole (Flagyl) because this combination can cause a serious reaction. Metronidazole (Flagyl) is available as a lower-cost generic.

Indications for Flagyl

Treatment of certain bacterial and parasitic infections, including:

Pros and Cons for Flagyl

Pros

  • Taken by mouth
  • Available as a lower-cost generic medication
  • Can be used to treat different types of bacterial infection
  • Immediate-release formulations can be taken with or without food

Cons

Common Side Effects for Flagyl

Please note: These are common side effects reported by people who took extended-release metronidazole (Flagyl)

  • Headache (18%)
  • Inflammation of the vagina (15%)
  • Nausea (10%)
  • Metallic taste (9%)
  • Flu-like symptoms (6%)

Warnings for Flagyl

  • Possible risk of cancer
  • Serious allergic reactions
  • Brain and nerve problems
  • Liver and kidney problems
  • Risk of fungal infection
  • Risk of drug resistance
  • Lower white blood cell counts
  • Interaction with other medications

Prices with our coupons for Gentamicin vs. Flagyl

Price Card Drug Icon
Gentamicin2 tubes / 15g of 0.1%
$31.50$99.97
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Metronidazole14 tablets / 500mg
$10.73$14.75
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