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Lioresal vs. Norflex

Intrathecal baclofen (Lioresal) is a muscle relaxant. It's given to adults and children ages 4 years and older to treat severe spasticity caused by certain conditions, like spinal cord injuries, that can't be treated with oral baclofen. Intrathecal baclofen (Lioresal) is typically given as a continuous infusion through an implantable pump. But before you can undergo the procedure to receive the pump, your healthcare team will inject test doses of intrathecal baclofen (Lioresal) to see if it works for you. Some side effects of this medication include nausea, sleepiness, and dizziness.

• Severe spasticity in people who are either having too many side effects from oral baclofen or who aren't getting enough symptom relief from it

• Muscle weakness (up to 35%)
• Sleepiness (up to 21%)
• Headache (up to 11%)
• Nausea and vomiting (up to 11%)
• Convulsions (up to 10%)
• Dizziness (8%)
• "Pins and needles" feeling in arms and legs (up to 7%)
• Stiff muscles (up to 6%)
• Constipation (up to 5%)

• Withdrawal when stopping intrathecal baclofen (Lioresal) suddenly
• Intrathecal baclofen overdose
• Worsening of other health conditions
• Extreme sleepiness or dizziness
• Ovarian cysts

Orphenadrine citrate is a muscle relaxer that's used to relieve muscle pain and discomfort. It's often used together with other pain-relieving methods, such as resting and physical therapy. Orphenadrine is available as a tablet that's taken by mouth as well as an injection that's administered by a healthcare provider for certain situations. Side effects can include dry mouth, headache, and drowsiness. Orphenadrine is a generic medication; its brand-name version, Norflex, is no longer available.

• Relief of muscle discomfort from short-term muscle conditions

• Dry mouth
• Sleepiness
• Headache
• Dizziness

• Difficulty concentrating
• Use with caution in people with heart problems