Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Metaxalone (Skelaxin) and carisoprodol (Soma) are both muscle relaxants used to treat muscle pain and discomfort, but they have some key differences. Metaxalone is not a controlled substance and is less likely to cause drowsiness compared to other muscle relaxers. It is typically taken three to four times a day and is available as a lower-cost generic. On the other hand, carisoprodol is a Schedule IV controlled substance due to its potential for misuse and dependence. It is usually taken three times a day and at bedtime, but only for short-term use (up to 2 to 3 weeks). Carisoprodol can cause significant drowsiness and has a higher risk of side effects like seizures, especially when combined with alcohol or other habit-forming substances. Neither medication should not be mixed with alcohol and both can cause dizziness and drowsiness, but carisoprodol has stricter usage guidelines due to its potential for addiction.
Metaxalone
Carisoprodol (Soma)
Metaxalone
Carisoprodol (Soma)
Summary of Skelaxin vs. Soma
Summary for Muscle relaxant
Prescription only
Metaxalone is a muscle relaxer. It's used to treat muscle pain and discomfort that's not chronic or long-lasting. This medication is thought to relieve muscle pain by relaxing your nervous system in the brain. Metaxalone is typically taken by mouth three or four times a day. It commonly causes drowsiness and dizziness as side effects. It's best to avoid drinking alcohol while you're taking metaxalone because alcohol can interact with this medication and worsen side effects.
Summary for Muscle relaxant
Prescription only
Carisoprodol (Soma) is a muscle relaxant that's used to treat muscle pain and discomfort in people ages 16 to 64. The tablets are approved for short-term treatment only and should only be taken for up to 2 to 3 weeks. Researchers think the medication relaxes muscles by changing nerve activity in your nervous system. Carisoprodol (Soma) is a controlled substance because it has a risk for misuse and dependence. Common side effects include headaches, dizziness, and sleepiness.
Indications of Skelaxin vs. Soma
Indications for
•Muscle discomfort caused by acute (not chronic) conditions when rest or physical therapy isn't enough for relief
Indications for
•Discomfort caused by painful muscle-related conditions (short-term only)