Carisoprodol (Soma) is a muscle relaxant that's used to treat muscle pain and discomfort in people ages 16 to 64. The tablets are approved for short-term treatment only and should only be taken for up to 2 to 3 weeks. Researchers think the medication relaxes muscles by changing nerve activity in your nervous system. Carisoprodol (Soma) is a controlled substance because it has a risk for misuse and dependence. Common side effects include headaches, dizziness, and sleepiness.
Discomfort caused by painful muscle-related conditions (short-term only)
Carisoprodol (Soma) is a muscle relaxant. The way it works to relieve muscle tension isn't well-understood. But the medication is thought to relax muscles by affecting the nerve activity in the brain and spinal cord.
Carisoprodol (Soma) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Risk factors: Age 65 years or older | Drinking alcohol | Taking other medications that cause drowsiness
Taking carisoprodol (Soma) can make you feel sleepy and have trouble concentrating or focusing. This is more likely to happen if you're over age 65 or if you take other medications that cause drowsiness. Don't drink alcohol while you're taking carisoprodol (Soma). Avoid activities that require you to be alert, like driving or operating machinery, until you know how this medication affects you.
Risk factors: History of substance use disorder | Taking more carisoprodol (Soma) than prescribed | Taking carisoprodol (Soma) for a long time | Stopping carisoprodol (Soma) suddenly
Only take carisoprodol (Soma) as instructed by your prescriber. Carisoprodol (Soma) has a risk for misuse. Misuse raises the risk for serious and life-threatening issues like having too much medication in the body and very slow breathing.
In addition, people who take carisoprodol (Soma) for a longer time than recommended are at higher risk for dependence. And people who suddenly stop carisoprodol (Soma) after taking it regularly might have symptoms of withdrawal, including trouble sleeping, stomach cramps, headache, and hallucinations (seeing or hearing things that aren't there). Ask your prescriber about how to safely stop taking carisoprodol (Soma).
Risk factors: Taking more carisoprodol (Soma) than prescribed | Taking high doses of other habit-forming medications | Taking carisoprodol (Soma) with alcohol
Though rare, some people who've taken carisoprodol (Soma) have had seizures. Most of these people either took too much medication (an overdose) or took their regular dose of carisoprodol (Soma) at the same time as alcohol or other habit-forming substances, such as opioids, benzodiazepines, or sleep aids.
Avoid alcohol until you're no longer taking carisoprodol (Soma). Ask your prescriber or pharmacist about how to safely take carisoprodol (Soma) with your other medications if they also have a risk for becoming habit-forming. Your prescriber might decide to choose a different muscle relaxer to be safe.
Source: DailyMed
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Incidence not known
Black, tarry stools
chills
cold sweats
confusion
convulsions
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
fast, pounding, or irregular heartbeat or pulse
loss of bladder control
muscle spasm or jerking of all extremities
painful or difficult urination
shortness of breath
sores, ulcers, or white spots on the lips or in the mouth
sudden loss of consciousness
swollen glands
unusual bleeding or bruising
unusual tiredness or weakness
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
Bigger, dilated, or enlarged pupils (black part of the eye)
blurred vision
change in consciousness
confusion as to time, place, or person
difficult or troubled breathing
false or unusual sense of well-being
hallucinations
headache
holding false beliefs that cannot be changed by fact
inability to move the eyes
increased blinking or spasms of the eyelid
increased sensitivity of the eyes to light
irregular, fast or slow, or shallow breathing
loss of consciousness
muscle stiffness or tightness
pale or blue lips, fingernails, or skin
sticking out of the tongue
trouble with breathing, speaking, or swallowing
uncontrolled eye movements
uncontrolled twisting movements of the neck, trunk, arms, or legs
unusual excitement, nervousness, or restlessness
unusual facial expressions
weakness of the arms and legs
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Drowsiness
Incidence not known
deep or fast breathing with dizziness
face is warm or hot to touch
fainting feeling of constant movement of self or surroundings
irritability
nervousness
numbness of the feet, hands, and around the mouth
pain or discomfort in the chest, upper stomach, or throat
redness to face
restlessness
sensation of spinning
shakiness and unsteady walk
trouble sleeping
unable to sleep
unsteadiness, trembling, or other problems with muscle control or coordination
vomiting
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Works quickly (generally within 30 minutes) to relieve muscle pain and discomfort
Available in two different strengths
Available as a lower-cost generic
Not a first-choice option for muscle pain
Typically taken four times daily
Can be habit-forming
Unknown if it's safe for people younger than age 16 or older than age 65
Carisoprodol (Soma) should only be used for a short period of time (up to 2 to 3 weeks). It's not meant to treat long-term pain. Ask a healthcare professional (HCP) about a better alternative for you if you have ongoing muscle spasms.
You can take carisoprodol (Soma) with or without food. Food won't affect how the medication works.
Carisoprodol (Soma) can affect your ability to focus and concentrate. Avoid driving or performing any activity that requires a lot of attention until you know how this medication affects you.
Side effects like dizziness and sleepiness are common. Don't drink alcohol while you're taking carisoprodol (Soma). Alcohol can make these side effects worse.
Tell your care team if you take other medications that cause dizziness or drowsiness, such as opioids, benzodiazepines, or sleep aids. Carisoprodol (Soma) can cause extreme drowsiness or dangerous breathing problems when it's combined with these other medications.
Also tell your care team and pharmacist about all the other medications that you take, including over-the-counter products, vitamins, and herbals. Carisoprodol (Soma) interacts with several common medications, including omeprazole (Prilosec), aspirin, and St. John’s Wort. Your care team can check that carisoprodol (Soma) is safe to take with your other medications.
If you've been taking carisoprodol (Soma) every day for a long period of time, don't stop taking it without talking to your prescriber first. This medication can cause withdrawal symptoms like hallucinations (seeing or hearing things that aren't there), vomiting, and stomach cramps. Your prescriber will work with you to lower your dose safely over time before you can completely stop the medication.
Store carisoprodol (Soma) up and away from children, pets, and visitors. Call a Poison Center at 1-800-222-1222 right away or go to the emergency room if you or someone you know accidentally took carisoprodol (Soma).
Adults and children between the ages of 16 and 64 years old: The typical recommended dose is 250 mg to 350 mg by mouth three times a day and at bedtime for no more than 2 to 3 weeks.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
History of acute intermittent porphyria (a rare blood condition)
Discomfort caused by painful muscle-related conditions (short-term only)
Muscle discomfort caused by acute (not long-term) conditions
Muscle discomfort caused by acute (not chronic) conditions when rest or physical therapy isn't enough for relief
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Conermann, T., et al. (2023). Carisoprodol. StatPearls.
Lewandowski, T.A. (2016). Pharmacokinetic modeling of carisoprodol and meprobamate disposition in adults. Human & Experimental Toxicology.
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Qaseem, A., et al. (2020). Nonpharmacologic and pharmacologic management of acute pain from non–low back, musculoskeletal injuries in adults: A clinical guideline from the American College of Physicians and American Academy of Family Physicians. Annals of Internal Medicine.
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