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Dulera vs. Advair

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Dulera (mometasone/formoterol) and Advair (fluticasone/salmeterol) are both inhaled medications used for the maintenance treatment of asthma. They belong to the same drug class, combining an inhaled corticosteroid (ICS) with a long-acting beta agonist (LABA) to help you breathe better. However, they have some differences. Dulera is only approved for asthma, while Advair Diskus is also approved for chronic obstructive pulmonary disease (COPD). Dulera is typically taken as 2 puffs twice daily, while Advair Diskus is usually 1 inhalation twice daily, and Advair HFA is 2 puffs twice daily. Advair is available in generic form as Wixela Inhub, but Dulera does not yet have a generic version. Common side effects of Dulera include cold symptoms and headache, while Advair can cause upper respiratory infections and sore throat. Both medications can lead to oral thrush, so it's important to rinse your mouth after use.

Dulera

(mometasone / formoterol)

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Advair

(fluticasone / salmeterol)

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Summary for Dulera

Prescription only

Dulera (mometasone / formoterol) is an inhaler that's used for the maintenance treatment of asthma in adults and children. It's a combination medication containing an inhaled corticosteroid (ICS) and a long-acting beta agonist (LABA) that work together to help make breathing easier. Dulera (mometasone / formoterol) is inhaled through the mouth twice per day. But the specific dosage depends on how old you are and how severe your asthma symptoms are. Side effects include common cold symptoms and headache. This medication isn't available as a lower-cost generic yet.

Indications for Dulera

  • Maintenance treatment of asthma in people ages 5 years and older

Pros and Cons for Dulera

Pros

  • Works well to improve lung function and lessen asthma symptoms
  • Combines two different asthma medications into a single inhaler for convenience
  • Can use with a spacer if you have trouble using the inhaler

Cons

  • Doesn't replace your rescue inhaler
  • Need to inhale 2 puffs twice daily for it to work well
  • Can raise your risk for infections

Common Side Effects for Dulera

Warnings for Dulera

  • Not for use for asthma attack or worsening breathing
  • Fungal infection in the mouth (oral thrush)
  • Sudden narrowing of your airways (bronchospasm)
  • Higher risk of infections
  • Caution when switching from oral to inhaled steroids
  • Changes in stress hormone levels
  • Heart problems
  • Delayed growth in children
  • Eye and vision problems
  • Low potassium levels in the blood

Summary for Advair

Prescription only

Advair is a combination inhaler that contains fluticasone (an inhaled corticosteroid) and salmeterol (a long-acting beta agonist, or LABA). Advair Diskus is used for maintenance treatment of chronic obstructive pulmonary disease (COPD) and asthma in adults and children, where as Advair HFA is for asthma only. Advair (fluticasone / salmeterol) is inhaled through the mouth, typically 1 to 2 puffs twice daily. Some common side effects of this medication include upper respiratory tract infection, sore throat, and headache.

Indications for Advair

  • Maintenance treatment of asthma
  • Maintenance treatment of COPD - Advair Diskus 250/50 only

Pros and Cons for Advair

Pros

  • Works well to lower the risk of asthma or COPD symptoms
  • Combines two medications into a single inhaler for convenience
  • Available as two different types of inhalers (Advair Diskus and Advair HFA)

Cons

  • Can cause fungal infections (thrush) in your mouth and throat
  • Advair Diskus contains lactose, so it might not be safe for people with severe milk protein allergies
  • Doesn't replace your rescue inhaler

Common Side Effects for Advair

Advair Diskus:

  • Upper respiratory infection (up to 27%)
  • Sore throat (up to 13%)
  • Headache (up to 13%)
  • Bronchitis (up to 8%)
  • Cough (up to 6%)
  • Nausea and vomiting (up to 6%)
  • Hoarseness (up to 5%)

Advair HFA:

  • Upper respiratory infection (up to 24%)
  • Headache (up to 21%)
  • Throat irritation (up to 9%)
  • Muscle and bone pain (up to 7%)
  • Nausea and vomiting (up to 5%)

Warnings for Advair

  • Not for use in asthma attack or for worsening breathing
  • Fungal infection in the mouth
  • Narrowing of your airways (bronchospasm)
  • Higher risk of infections
  • Altered stress hormone levels
  • Delayed growth in children
  • Eye and vision problems
  • Heart problems
  • Low potassium levels in the blood
  • Allergic reactions

Prices with our coupons for Dulera vs. Advair

Price Card Drug Icon
Dulera1 inhaler / 120 doses of 200mcg/5mcg
$199.00$407.98
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Price Card Drug Icon
Fluticasone/Salmeterol1 diskus inhaler / 250mcg/50mcg
$65.46$314.99
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