Key takeaways
Sotalol (Betapace) and bisoprolol (Zebeta) are both beta blockers, but they have some key differences. Sotalol is a non-selective beta blocker and potassium channel blocker used to treat and prevent certain heart rhythm problems like atrial fibrillation. It requires close monitoring in a hospital when you first start taking it. Bisoprolol, on the other hand, is a selective beta blocker primarily used to treat high blood pressure and is usually taken once a day. Sotalol can cause serious side effects like abnormal heart rhythms and breathing problems, especially in people with asthma or COPD. Bisoprolol is less likely to cause breathing issues but can still worsen heart failure if not managed properly. Both medications are available in generic forms, but bisoprolol is not a first-choice treatment for high blood pressure and is typically used when other medications aren't effective. Additionally, bisoprolol can interact with alcohol, increasing the risk of dizziness and fainting.
