Key takeaways
Ipratropium (Atrovent) and fluticasone (Flonase, Flonase Sensimist) nasal sprays are both used to treat runny noses caused by allergies. However, they belong to different medication classes. Ipratropium is an anticholinergic that works by blocking acetylcholine to reduce mucus production, while fluticasone is a corticosteroid that reduces inflammation in the nose. Ipratropium is available only by prescription and comes in generic form, whereas fluticasone is available both by prescription and over-the-counter. Ipratropium is typically used multiple times a day, while fluticasone is usually taken once daily. Common side effects of ipratropium include headaches and nosebleeds, while fluticasone may cause headaches, sore throats, and nosebleeds. Fluticasone can also slow growth in children if used for more than two months a year. Ipratropium may not be safe for people with glaucoma or prostate problems, while fluticasone can increase the risk of eye problems and infections.
