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Compare Duoneb vs. Combivent

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Duoneb (ipratropium/albuterol) and Combivent Respimat (ipratropium/albuterol) are both used to treat chronic obstructive pulmonary disease (COPD) and contain the same active ingredients, but they differ in their form and administration. Duoneb is an inhalation solution that you use with a nebulizer, while Combivent Respimat is an inhaler, making it more convenient. Duoneb typically requires 4 doses a day, with each session taking up to 15 minutes, while Combivent Respimat also requires 4 doses a day but only takes a few seconds per dose. Both medications can cause similar side effects, such as lung problems and heart issues. Duoneb is available as a generic, making it a more affordable option, whereas Combivent Respimat is only available as a brand medication and can be expensive.

  • Ipratropium/albuterol solution
    Combivent respimat (ipratropium / albuterol)
  • Ipratropium/albuterol solution
    Combivent respimat (ipratropium / albuterol)

  • Summary of Duoneb vs. Combivent

    Summary for SAMA / SABA
    Prescription only

    Ipratropium bromide/albuterol sulfate is a combination inhalation solution made up of two different bronchodilators. This combination is used to treat chronic obstructive pulmonary disease (COPD) in adults. It's inhaled through a nebulizer, typically 4 times a day. Side effects of this medication include lung problems, sore throat, and chest pain. The brand name Duoneb has been discontinued, so ipratropium/albuterol solution is only available as a generic.

    Summary for SAMA / SABA
    Prescription only

    Combivent Respimat is an inhaler that's used to treat chronic obstructive pulmonary disease (COPD) in adults. It's a combination medication that contains two different bronchodilators: ipratropium, a short-acting muscarinic antagonist (SAMA), and albuterol, a short-acting beta agonist (SABA). The medication is inhaled through the mouth 4 times a day, but up to 6 times per day if instructed. Combivent Respimat (ipratropium / albuterol) isn't a rescue inhaler; it's used regularly rather than as needed for sudden breathing problems. Side effects aren't common but can include upper respiratory tract infections and cough.

  • Indications of Duoneb vs. Combivent

    Indications for
    •Treatment of shortness of breath in people with chronic obstructive pulmonary disease (COPD) who need more than one bronchodilator
    Indications for
    •Maintenance treatment for chronic obstructive pulmonary disease (COPD) in adults who need more than one bronchodilator

  • Pros and Cons of Duoneb vs. Combivent

    Pros and Const for SAMA / SABA
    Pros
    •Starts working within minutes
    •More convenient to use a combination of two bronchodilators in a single medication
    •Available as a lower-cost generic
    Cons
    •Need to use with a nebulizer machine, which can be inconvenient
    •Takes up to 15 minutes to receive the whole dose
    •Might not be a good option for those with heart problems
    Pros and Const for SAMA / SABA
    Pros
    •Combines two different bronchodilators within a single inhaler for convenience
    •Can start to work in about 15 minutes to help with breathing for some people
    •Doesn't require shaking before use
    •Don't need to rinse your mouth after use
    Cons
    •Not a rescue inhaler
    •Might need to use up to 6 times per day, depending on the severity of your COPD symptoms
    •Might not be a good option for people with heart problems
    •No lower-cost generic; only available as a brand-name medication

  • Common Side Effects of Duoneb vs. Combivent

    Common Side Effects for
    •Lung problems (6%)
    •Sore throat (4%)
    •Chest pain (3%)
    •Bronchitis (2%)
    •Diarrhea (2%)
    •Urinary tract infection (2%)
    Common Side Effects for
    •Common cold symptoms (4%)
    •Upper respiratory infection (3%)
    •Cough (3%)
    •Bronchitis (3%)
    •Headache (3%)

  • Warnings of Duoneb vs. Combivent

    Common Side Effects for
    •Narrowing of your airways (bronchospasm)
    •Heart problems
    •Eye problems
    •Trouble urinating
    •Severe allergic reactions
    •Low potassium in the blood
    Common Side Effects for
    •Narrowing of the airways (bronchospasm)
    •Effects on the heart and blood pressure
    •Eye problems
    •Trouble urinating
    •Severe allergic reaction
    •Low potassium in the blood

  • Prices with our coupons for Duoneb vs. Combivent

    Learn more about Ipratropium/albuterol solution
    Learn more about Combivent respimat

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