Key takeaways
Aripiprazole (Abilify) and quetiapine (Seroquel) are both atypical antipsychotics used to treat mental health conditions like schizophrenia and bipolar disorder. Aripiprazole is available in various forms, including oral tablets, solutions, and orally disintegrating tablets, and can be used in children as young as 6 years old for certain conditions. Quetiapine, on the other hand, comes in immediate-release and extended-release tablets and is also used for depression when combined with another antidepressant. Aripiprazole is less likely to cause weight gain compared to other antipsychotics, while quetiapine is more likely to raise blood triglyceride levels and cause weight gain. Both medications can cause serious side effects like neuroleptic malignant syndrome and difficulty controlling movements, and carry a risk of causing suicidal thoughts, especially in people under 24. Additionally, quetiapine can affect heart rhythm and is not recommended for older adults with dementia-related psychosis. Both medications are available in generic forms, making them more affordable options.
