Nonselective alpha-beta blockers are used to treat high blood pressure. They also have other uses, such as treating heart failure and protecting the heart after a heart attack. These medications work by blocking the alpha and beta receptors on your heart and blood vessels, which helps to slow your heart rate and lower your blood pressure. Nonselective alpha-beta blockers are available in oral forms, including extended-release options. Examples include carvedilol (Coreg, Coreg CR). You can choose the form that best fits your needs.