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Altreno Coupon - Altreno 45g of 0.05% tube of lotion

Altreno

tretinoin
Used for Acne

Altreno (tretinoin) is a prescription topical retinoid used to treat acne in adults and children 9 years and older. It comes as a lotion that's applied in a thin layer to the affected skin once a day. Common side effects include dryness, burning or stinging, redness, irritation, and peeling where you apply it.

Reviewed by:Last reviewed on October 19, 2026
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What is Altreno (tretinoin)?

What is Altreno (tretinoin) used for?

How Altreno (tretinoin) works

Altreno (tretinoin) is a retinoid, which is a form of vitamin A. The exact way it treats acne isn't fully understood, but it helps prevent dead skin cells from sticking together and clogging your pores. It also helps clear clogged pores, which reduces blackheads, whiteheads, and other acne.

When does Altreno (tretinoin) start working?Time passed since treatment started:
HOURS
DAYS
WEEKS
Initial effect
MONTHS
Full effect

Drug facts

Common BrandsAltreno
Drug ClassRetinoid
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
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Side effects of Altreno (tretinoin)

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Dry skin at application site (4%)
  • Pain at application site (3%)
  • Redness at application site (2%)

Less Common Side Effects

  • Irritation at application site
  • Peeling at application site

Altreno (tretinoin) serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Severe allergic reaction: hives, severe itching, swelling, trouble breathing

Source: DailyMed

The following Altreno (tretinoin) side effects have also been reported

Side effects that you should report to your care team as soon as possible:

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • Change in skin color
  • Mild skin irritation, redness, or dryness
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Pros and cons of Altreno (tretinoin)

Pros

  • Only applied once daily
  • Lotion formulation designed to reduce skin irritation
  • Approved for adults and children ages 9 years and older

Cons

  • Acne can take several weeks to improve
  • Can make your skin more sensitive to sunlight
  • Might not be the best option for people with fish allergies
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Pharmacist tips for Altreno (tretinoin)

pharmacist
  • Use Altreno (tretinoin) once a day, even if your acne doesn't improve right away. Acne treatments take time to work, so use it regularly for the best results.
  • Altreno (tretinoin) can cause dryness, redness, burning, or peeling. A moisturizer can help soothe your skin, but contact your prescriber if irritation is severe or doesn't improve.
  • Altreno (tretinoin) can make your skin more sensitive to sunlight. Avoid tanning beds and sunlamps, and use sunscreen and wear protective clothing when you're outside.
  • You can wear makeup with Altreno (tretinoin). Just make sure to apply the medication first and let it dry before putting makeup on.
  • Pregnancy: Altreno (tretinoin) generally isn't recommended during pregnancy. Talk to a healthcare professional about the risks and benefits if you're pregnant or planning to become pregnant.
  • Breastfeeding: Only a small amount of Altreno (tretinoin) is expected to enter your body through your skin, so it's considered low risk while breastfeeding. Talk to your prescriber before using it while breastfeeding.

How to use Altreno (tretinoin)

  • Before you apply the medication, gently wash your skin and pat it dry.
  • Altreno (tretinoin) comes in a tube and pump. Squeeze or pump the lotion onto your fingertip.
  • Apply a thin layer over the affected area(s) of your skin, spreading the lotion evenly.
  • Wash your hands after applying the lotion, unless your hands are the area being treated. This helps prevent accidentally getting the medication in your eyes or other sensitive areas.
  • Don't apply the lotion to broken, sunburned, or eczema-affected skin. These areas can become more irritated.
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Risks and warnings for Altreno (tretinoin)

Altreno (tretinoin) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

Skin irritation

  • Risk factors: Sunburned or irritated skin | Eczema

Altreno (tretinoin) can cause dryness, redness, pain, peeling, or irritation where you apply it. Using a moisturizer can help with mild irritation. If your symptoms are severe or don't improve, your prescriber might recommend using the medication less often or stopping it.

Avoid applying Altreno (tretinoin) to sunburned skin or areas affected by eczema because this can make irritation worse.

Sun sensitivity

  • Risk factors: Spending a lot of time in the sun | Having skin that's sensitive to sunlight | Using sunlamps or tanning beds

Altreno (tretinoin) can make your skin more sensitive to sunlight. Limit time in the sun and avoid sunlamps and tanning beds during treatment. When you're outside, use sunscreen and wear protective clothing over treated skin.

Use with caution in people with fish allergies

  • Risk factors: Allergy to fish or fish-containing products

Altreno (tretinoin) contains fish proteins, which might cause an allergic reaction if you have a fish allergy. Tell your care team about any fish allergies before starting treatment. Contact them if you develop itching or hives after using the medication.

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Altreno (tretinoin) dosage

The average cost for 1 tube of 45g of 0.05% of Altreno (tretinoin) is $116.65 with a free GoodRx coupon. This is 10.18% off the average retail price of $129.87.
tube of lotionTube of lotion
DosageQuantityPrice as low asPrice per unit
45g of 0.05%1 tube$116.65$116.65
20g of 0.05%1 tube$54.25$54.25
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How much does Altreno (tretinoin) cost?

To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
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What are alternatives to Altreno (tretinoin)?

There are a number of medications that your doctor can prescribe in place of Altreno (tretinoin). Compare a few possible alternatives below.
Altreno (tretinoin)
Used for:
$54.25Lowest GoodRx priceView prices
Used for:
  • Acne
$10.09Lowest GoodRx priceView prices
Used for:
  • Treatment of papules and pustules in adults with mild-to-moderate rosacea
$36.03Lowest GoodRx priceView prices
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News about Altreno (tretinoin)

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Altreno (tretinoin) images

Yellow Not applicable - Altreno 0.05% Topical Lotion
This medicine is Yellow Tube Of Lotion.Yellow Not applicable - Altreno 0.05% Topical Lotion

References

Best studies we found

Bausch Health US. (2020). ALTRENO (tretinoin) lotion, 0.05% [package insert]. DailyMed.

Bhatia, N., et al. (2020). A split-face, controlled study to assess the compatibility of tretinoin 0.05% acne lotion with facial foundation makeup. Journal of Clinical and Aesthetic Dermatology.

Kircik, L. H., et al. (2019). Matrix revisited: Innovative approach for tretinoin. Journal of Drugs in Dermatology.

Drugs and Lactation Database (LactMed). (2024). Tretinoin.

MotherToBaby. (2024). Topical tretinoin.

U.S. Food and Drug Administration. (2018). Multi-disciplinary review and evaluation: ALTRENO (tretinoin) lotion, 0.05% for topical use.

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.