Skip to main content
Prednisone Coupon - Prednisone 20mg tablet

prednisone

Generic Deltasone
Used for Adrenal Insufficiency, Allergic Conjunctivitis, Allergic Rhinitis, Asthma, Chronic ITP, Eczema, Edema, Eye Inflammation, Gout, Leukemia, Lupus, Multiple Sclerosis, Non-Hodgkin Lymphoma, Osteoarthritis, Psoriasis, Psoriatic Arthritis, Rheumatoid Arthritis, Seborrheic Dermatitis, Skin Allergy, Tuberculosis, Ulcerative Colitis

Prednisone is a corticosteroid medication used to treat various conditions in pets, including autoimmune conditions, allergies, Addison’s disease, and certain cancers. It works by reducing inflammation and calming an overactive immune system. It’s commonly prescribed for dogs, but not usually for cats because cats don’t absorb the medication well. It comes in tablet and liquid forms and is given by mouth. Common side effects include increased appetite, thirst, and urination.

Reviewed by:Last reviewed on April 25, 2025
Paws

For pets

Prednisone can be prescribed or used off-label by a licensed veterinarian for pets. Medications prescribed for pets aren't intended for human use.

basics-icon

What is Prednisone for pets?

What is Prednisone for pets used for?

How Prednisone for pets works

Prednisone is a corticosteroid. It acts like your pet’s natural hormone called cortisol. The medication works by calming down the immune system when it’s too active, which can treat inflammatory conditions like allergies or autoimmune diseases. The medication also replaces natural steroids if your pet’s body isn’t making enough, like in Addison’s disease.

Drug facts

Common BrandsDeltasone
Drug ClassCorticosteroid
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
side-effects-icon

Side effects of Prednisone for pets

The following side effects might get better over time as your pet gets used to the medication. Let your veterinarian know immediately if your pet continues to experience these symptoms or if they worsen over time.

Common Side Effects

  • Extreme thirst
  • Increased appetite
  • Frequent urination
  • Weight gain
  • Panting
  • Restlessness

Less Common Side Effects

  • Vomiting
  • Diarrhea
  • Behavior changes

Prednisone serious side effects

Contact your veterinarian immediately if your pet experiences any of the following.

  • Stomach or intestinal ulcers: vomiting, diarrhea, reduced appetite, weight loss, black stools
  • Infections: fever, shaking, vomiting, diarrhea, tiredness
  • Cushing’s disease: increased thirst, increased appetite, frequent urination, weight gain, tiredness, hair loss, pot belly

The following Prednisone side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Aggression

agitation

blurred vision

decrease in the amount of urine

dizziness

fast, slow, pounding, or irregular heartbeat or pulse

headache

irritability

mood changes

noisy, rattling breathing

numbness or tingling in the arms or legs

pounding in the ears

shortness of breath

swelling of the fingers, hands, feet, or lower legs

trouble thinking, speaking, or walking

troubled breathing at rest

weight gain

Incidence not known

Abdominal or stomach cramping or burning (severe)

abdominal or stomach pain

backache

bloody, black, or tarry stools

cough or hoarseness

darkening of the skin

decrease in height

decreased vision

diarrhea

dry mouth

eye pain

eye tearing

facial hair growth in females

fainting

fever or chills

flushed, dry skin

fractures

fruit-like breath odor

full or round face, neck, or trunk

heartburn or indigestion (severe and continuous)

increased hunger

increased thirst

increased urination

loss of appetite

loss of sexual desire or ability

lower back or side pain

menstrual irregularities

muscle pain or tenderness

muscle wasting or weakness

nausea

pain in the back, ribs, arms, or legs

painful or difficult urination

skin rash

sweating

trouble healing

trouble sleeping

unexplained weight loss

unusual tiredness or weakness

vision changes

vomiting

vomiting of material that looks like coffee grounds

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Increased appetite

Incidence not known

Abnormal fat deposits on the face, neck, and trunk

acne

dry scalp

lightening of normal skin color

red face

reddish purple lines on the arms, face, legs, trunk, or groin

swelling of the stomach area

thinning of the scalp hair

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

prices-container

Get your GoodRx coupon

Avg retail price
$19.06(Save 61.86%)
GoodRx discount
$7.27
See prices
pros-and-cons-icon

Pros and cons of Prednisone for pets

Pros

  • Treats many different conditions
  • Most pets only need a short course of medication
  • Comes in tablet and liquid forms

Cons

  • Long-term use can lead to serious side effects
  • Might need to slowly lower the dose before stopping
  • Doesn’t work as well as prednisolone in cats
pharmacist-tips-icon

Pharmacist tips for Prednisone for pets

pharmacist
  • You can give prednisone with food to help lower the chance of an upset stomach.
  • Prednisone can cause trouble sleeping. For dogs, giving the medication in the morning might help them sleep better at night. Since cats are more active at night, it might be better to give it to them in the evening instead.
  • Keep plenty of fresh water available while your pet is taking prednisone. Increased thirst is a common side effect and your pet might drink and urinate more than usual.
  • If your pet takes the liquid form of prednisone, use a measuring spoon or syringe to give the correct dose. Don’t use household spoons since they come in different sizes and might give the wrong amount.
  • Prednisone shouldn’t be given to pregnant animals unless the benefits are greater than the risks. Talk to your vet if your pet becomes pregnant or if you plan to breed your pet while they’re taking this medication.
  • Your pet might need to taper off prednisone — this means starting with a higher dose and slowly lowering it. Follow your vet’s instructions carefully to help prevent withdrawal and keep your pet safe.
warnings-icon

Risks and warnings for Prednisone for pets

Prednisone can cause some serious health issues. This risk might be even higher for certain pets. If this worries you, talk to your veterinarian about other options.

Stomach or intestinal ulcers

  • Risk factors: Taking other medications that cause stomach or intestinal ulcers

Prednisone can sometimes cause stomach or intestinal ulcers in pets, especially if taken with other medications that raise your risk for these ulcers. These ulcers can lead to serious problems like vomiting, reduced appetite, diarrhea, or bloody stool. If your pet shows any of these signs, contact your vet right away.

Infections

Prednisone can weaken your pet’s immune system, making it harder for them to fight off infections that normally wouldn’t be a problem. While taking this medication, your pet might be at risk for bacterial, fungal, or parasitic infections. Contact your vet right away if your pet shows signs of infection, such as fever, vomiting, diarrhea, shaking, weakness, or confusion.

Cushing’s disease

  • Risk factors: Long-term steroid treatment | High doses of prednisone

If your pet takes prednisone at a high dose or for a long time, they might be at higher risk for Cushing’s disease. Signs to watch for include drinking and eating more than usual, urinating more often, a round “pot-bellied” stomach, low energy, and hair loss. If you see any of these symptoms, call your vet. They might give you instructions on how to slowly lower the dose. Never stop this medication suddenly since it could cause withdrawal symptoms.

dosage-icon

Prednisone dosage forms for pets

The average cost for 10 tablets of 20mg of Prednisone is $7.27 with a free GoodRx coupon. This is 61.86% off the average retail price of $19.06.
dose packDose pack
DosageQuantityPrice as low asPrice per unit
21 tablets of 10mg1 dose pack$11.18$11.18
48 tablets of 10mg1 dose pack$22.09$22.09
21 tablets of 5mg1 dose pack$15.34$15.34
48 tablets of 5mg1 dose pack$11.37$11.37
ml of oral solutionMl of oral solution
DosageQuantityPrice as low asPrice per unit
5mg/5ml50 ml$20.68$0.41
tabletTablet
DosageQuantityPrice as low asPrice per unit
2.5mg90 tablets$14.63$0.16
20mg10 tablets$7.27$0.73
1mg90 tablets$13.03$0.14
10mg30 tablets$7.85$0.26
5mg30 tablets$8.98$0.30
50mg5 tablets$7.35$1.47

Typical dosage for Prednisone

The dose will depend on your pet’s weight and the condition being treated.

  • Dogs:

    • Allergies: The typical dose is 0.5 mg/kg to 1 mg/kg per day given by mouth.
    • Autoimmune conditions: The typical dose is around 2 mg/kg per day by mouth.
    • Addison’s disease: The typical dose is less than 0.1 mg/kg to 0.25 mg/kg per day by mouth.
  • Cats:

    • See the dosage for prednisolone. Cats usually receive prednisolone instead of prednisone, but if your cat is prescribed prednisone, the dose will likely be similar to the prednisolone dose.
interactions-icon

Interactions between Prednisone and other drugs for pets

Prednisone might interact with certain medications or supplements. Always let your veterinarian know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that your pet is currently taking. The list below does not include all possible drug interactions with Prednisone. Please note that only the generic name of each medication is listed below.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

cost-icon

How much does Prednisone cost?

To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
contraindications-icon

Prednisone contraindications for pets

Contraindications are specific health conditions or situations in which a pet should not take a medication due to safety concerns. If your pet has any of the following conditions or if any of the following apply to your pet, let your veterinarian know because Prednisone will not be safe for your pet to take.

  • Fungal infections spread throughout the body
  • Stomach or intestinal ulcers
  • Untreated Cushing’s disease
latest-news-icon

News about Prednisone

images-icon

Prednisone images

White Round 54 760 - Prednisone 20mg Tablet
This medicine is White, Round, Scored Tablet Imprinted With "54 760".White Round 54 760 - Prednisone 20mg Tablet
Peach Round Dan Dan And 5443 - Prednisone 20mg Tablet
This medicine is Peach, Round, Scored Tablet Imprinted With "5443" And "Dan Dan".Peach Round Dan Dan And 5443 - Prednisone 20mg Tablet
Peach Round 50 92 And V - Prednisone 20mg Tablet
This medicine is Peach, Round, Scored Tablet Imprinted With "50 92" And "V".Peach Round 50 92 And V - Prednisone 20mg Tablet
Peach Round Tl 175 - Prednisone 20mg Tablet
This medicine is Peach, Round, Scored Tablet Imprinted With "Tl 175".Peach Round Tl 175 - Prednisone 20mg Tablet
White Round Ac72 - Prednisone 20mg Tablet
This medicine is White, Round, Scored Tablet Imprinted With "Ac72".White Round Ac72 - Prednisone 20mg Tablet
White Round Ac72 - Prednisone 20mg Tablet
This medicine is White, Round, Scored Tablet Imprinted With "Ac72".White Round Ac72 - Prednisone 20mg Tablet
White Round Ce 127 - Prednisone 20mg Tablet
This medicine is White, Round, Scored Tablet Imprinted With "Ce 127".White Round Ce 127 - Prednisone 20mg Tablet
White Round Ce 127 - Prednisone 20mg Tablet
This medicine is White, Round, Scored Tablet Imprinted With "Ce 127".White Round Ce 127 - Prednisone 20mg Tablet
White Round E 173 - Prednisone 20mg Tablet
This medicine is White, Round, Scored Tablet Imprinted With "E 173".White Round E 173 - Prednisone 20mg Tablet
White Round E 173 - Prednisone 20mg Tablet
This medicine is White, Round, Scored Tablet Imprinted With "E 173".White Round E 173 - Prednisone 20mg Tablet
White Round E 173 - Prednisone 20mg Tablet
This medicine is White, Round, Scored Tablet Imprinted With "E 173".White Round E 173 - Prednisone 20mg Tablet
White Round 060 - Prednisone 20mg Tablet
This medicine is White, Round, Scored Tablet Imprinted With "060".White Round 060 - Prednisone 20mg Tablet

References

Best studies we found

Blois, S. (2025). Gastrointestinal ulcers in small animals. Merck Manual Veterinary Manual.

Del Baldo, F., et al. (2024). Hypothalamic-pituitary-adrenal axis recovery after intermediate-acting glucocorticoid treatment in client-owned dogs. Journal of Veterinary Internal Medicine.

Edwards, S. H. (2024). Corticosteroids in animals. Merck Manual Veterinary Manual.

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.