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gabapentin

Generic Neurontin
Used for Epilepsy, Postherpetic Neuralgia
Used for Epilepsy, Postherpetic Neuralgia

Gabapentin, also known by its brand name Neurontin, is used to treat nerve pain from shingles in adults. This medication can also help treat partial (focal) seizures in adults and children. Gabapentin (Neurontin) comes as pills and a liquid that you take by mouth. The dosage depends on things like what you're treating, how old you are, and how well the medication is working. In general, you take it 3 times a day. Common side effects include making you feel dizzy and sleepy.

Last reviewed on October 29, 2025
basics-icon

What is Gabapentin (Neurontin)?

What is Gabapentin (Neurontin) used for?

How Gabapentin (Neurontin) works

Gabapentin (Neurontin) is a type of medication called an antiepileptic. We don't completely know how it works to treat nerve pain or seizures.

But we do know that gabapentin (Neurontin) has a similar structure to a brain chemical called gamma-aminobutyric acid (GABA). This chemical helps calm nerve activity in the brain. It's possible that mimicking GABA might help improve nerve pain and seizures. There might be other ways the medication works that researchers are still exploring.

When does Gabapentin (Neurontin) start working?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Initial effect
Full effect

Drug Facts

Common BrandsNeurontin
Drug ClassAntiepileptic
Controlled Substance ClassificationControlled in some states. See FAQs below.
Generic StatusLower-cost generic available
AvailabilityPrescription only

More on Gabapentin (Neurontin) essentials

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What are the side effects of Gabapentin (Neurontin)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Sleepiness (19%)
  • Dizziness (17%)
  • Poor muscle control or clumsiness (13%)
  • Fatigue (11%)

Other Side Effects

  • Indigestion
  • Constipation
  • Dry mouth
  • Dry throat
  • Swelling in arms or legs
  • Weight gain
  • Tremor
  • Uncontrollable eye movements (nystagmus)
  • Double vision
  • Changes in mood or behavior (children)
Note: Side effect percentages were reported from people 12 years and older with seizures. Percentages might differ for younger ages.

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Serious allergic reaction: hives; sudden rash; skin redness of the whole body, followed by peeling; swelling of the face, lips, or tongue; trouble breathing; fever
  • Suicidal thoughts or behaviors
  • _Very slowed breathing
When do Gabapentin (Neurontin) possible side effects begin and end?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Dizziness
Sleepiness
Poor muscle control

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Clumsiness or unsteadiness

continuous, uncontrolled, back-and-forth, or rolling eye movements

More common in children

Aggressive behavior or other behavior problems

anxiety

concentration problems and change in school performance

crying

depression

false sense of well-being

hyperactivity or increase in body movements

rapidly changing moods

reacting too quickly, too emotional, or overreacting

restlessness

suspiciousness or distrust

Less common

Black, tarry stools

chest pain

chills

cough

depression, irritability, or other mood or mental changes

fever

loss of memory

pain or swelling in the arms or legs

painful or difficult urination

sore throat

sores, ulcers, or white spots on the lips or in the mouth

swollen glands

unusual bleeding or bruising

unusual tiredness or weakness

Incidence not known

Abdominal or stomach pain

blistering, peeling, or loosening of the skin

clay-colored stools

coma

confusion

convulsions

dark urine

decreased urine output

diarrhea

difficult or troubled breathing

dizziness

fast or irregular heartbeat

headache

increased thirst

irregular, fast or slow, or shallow breathing

itching or skin rash

joint pain

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

loss of appetite

muscle ache or pain

nausea

pale or blue lips, fingernails, or skin

red skin lesions, often with a purple center

red, irritated eyes

unpleasant breath odor

vomiting of blood

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Blurred vision

cold or flu-like symptoms

delusions

dementia

hoarseness

lack or loss of strength

lower back or side pain

swelling of the hands, feet, or lower legs

trembling or shaking

Less common or rare

Accidental injury

appetite increased

back pain

bloated or full feeling

body aches or pain

burning, dry, or itching eyes

change in vision

change in walking and balance

clumsiness or unsteadiness

congestion

constipation

cough producing mucus

decrease in sexual desire or ability

dryness of the mouth or throat

earache

excess air or gas in the stomach or intestines

excessive tearing

eye discharge

feeling faint, dizzy, or lightheadedness

feeling of warmth or heat

flushed, dry skin

flushing or redness of the skin, especially on the face and neck

frequent urination

fruit-like breath odor

impaired vision

incoordination

increased hunger

increased sensitivity to pain

increased sensitivity to touch

increased thirst

indigestion

noise in the ears

pain, redness, rash, swelling, or bleeding where the skin is rubbed off

passing gas

redness or swelling in the ear

redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid

runny nose

sneezing

sweating

tender, swollen glands in the neck

tightness in the chest

tingling in the hands and feet

trouble sleeping

trouble swallowing

trouble thinking

twitching

unexplained weight loss

voice changes

vomiting

weakness or loss of strength

weight gain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Gabapentin (Neurontin)

thumbs-up

Pros

An option for relieving nerve pain caused by shingles

Can take with other anti-seizure medications for partial-onset seizures in people 3 years and older

Available as a tablet, capsule, and liquid for those who have trouble swallowing pills

thumbs-down

Cons

Usually need to taken three times per day

Can cause dizziness and sleepiness

Can cause withdrawal symptoms if you stop taking the medication too suddenly or too fast

pharmacist-tips

Pharmacist tips for Gabapentin (Neurontin)

pharmacist
  • Take gabapentin (Neurontin) with or without food.

    • For gabapentin (Neurontin) capsules: Swallow the capsules whole with water. Don't crush, chew, or open the capsules. If you have trouble swallowing them whole, talk to your prescriber about your options.

      • For gabapentin (Neurontin) tablets: If needed, you can split the tablets along the line down the middle. Use a pill splitter from the pharmacy to cut them evenly and safely. If you split a tablet, take the other half the next time you take your medication. Don't use half-tablets that have already been cut for more than 28 days.

        • For gabapentin (Neurontin) oral solution: Keep the liquid refrigerated. If you're given a bottle of medication, be sure to use a dosing cup or oral syringe to measure out the dose. Don't use household measuring cups or spoons because it can make you take or give the wrong dose. Ask the pharmacy if you have questions on how to measure out the liquid for your dose.

          • Gabapentin (Neurontin) often makes you dizzy and sleepy. These side effects can make it harder to think clearly and react quickly. Don't drive or do anything that needs your full attention until you know how this medication affects you.

            • Avoid drinking alcohol while taking gabapentin (Neurontin). Mixing alcohol with this medication can worsen side effects like sleepiness, dizziness, and slow breathing. This can be dangerous.

              • Tell your prescribers and pharmacist about all the medications you take or plan to take. Gabapentin (Neurontin) can interact with some medications, such as benzodiazepines and opioid medications. It can raise your risk of side effects, like sleepiness, dizziness, and dangerously slow breathing.

                • Take gabapentin (Neurontin) at least 2 hours after taking a medication that has aluminum or magnesium, like Mylanta Maximum Strength. These ingredients can lower how much gabapentin (Neurontin) your body absorbs. This can make gabapentin (Neurontin) work less well. Spacing out the medications helps make sure they work the way they should.

                  • Gabapentin (Neurontin) can raise the risk of having suicidal thoughts. Talk to your prescriber if you or your loved ones notice any new or worsening changes in your behavior or mood. And call 911 right away if you have any thoughts of harming yourself.

                    • Don't change your dose or stop taking gabapentin (Neurontin) suddenly without talking to your prescriber first. Otherwise, it can cause uncomfortable withdrawal symptoms like anxiety and agitation. If you take this medication for seizures, you could also have more seizures. Your prescriber can help you lower your dose slowly and safely.

                      More on Gabapentin (Neurontin) tips

                      faqs

                      Frequently asked questions about Gabapentin (Neurontin)

                      Is gabapentin (Neurontin) a controlled substance?
                      The federal government doesn't list gabapentin (Neurontin) as a controlled substance. But studies show that it can be potentially misused. Examples of misuse include taking it at high doses or not as prescribed for its ability to cause a "high" feeling. Because of this risk, some states classify gabapentin (Neurontin) as a controlled substance (schedule V). Other states don't, but they still keep track of prescriptions through a monitoring program. If you have questions about controlled substance laws in your state, it's best to talk to a local healthcare professional.
                      Does gabapentin (Neurontin) cause weight gain?
                      It's possible for you to gain weight while you're taking gabapentin (Neurontin). In general, it's not a common side effect, but it might be more likely to happen at higher doses. In studies, a small percentage of people who took the medication said they gained weight. But it's not clear how much weight they gained. Also keep in mind that some people had swelling due to extra fluid buildup in the body. This could appear as water weight. And, there could be other reasons for your weight gain, like changes to your diet or exercise routine. Talk to your care team about ways to manage your weight. Also ask them if you have more questions about gabapentin (Neurontin) and weight gain.
                      Does gabapentin (Neurontin) make you sleepy?
                      Yes, sleepiness is a common side effect of gabapentin (Neurontin). In studies, about 1 in 5 people who took the medication said they had felt sleepy. Make sure not to drive or do anything that you need to focus for until you know how this medication affects you. Let your prescriber know if you get too sleepy while taking gabapentin (Neurontin). They also might see if lowering your dose of gabapentin (Neurontin) can help.
                      Can you take gabapentin (Neurontin) for any type of nerve pain?
                      Gabapentin (Neurontin) is only FDA approved to treat nerve pain caused by shingles. But it's often prescribed off-label for other kinds of nerve pain. This can include nerve pain from diabetes, fibromyalgia, and sciatic nerve pain. These are uses are called off-label because they're different from what the medication was approved for. Gabapentin (Neurontin) can have safety risks. So, it's important to take it only for the condition the healthcare professional prescribed it for and exactly as directed. If you have new or worsening pain, talk to your primary care provider. They can help figure out what kind of pain you have and what treatment options there are for you.
                      How long does it take for gabapentin (Neurontin) to start working to treat nerve pain?
                      Gabapentin (Neurontin) can start to help with nerve pain within the first week. But it can sometimes take up to a month or longer for you to feel the full effects. Remember, it can take some time to find the right dose for you. You usually start gabapentin (Neurontin) at a lower dose. Then, your prescriber raises your dose slowly to help you get used to the medication. They'll adjust the dose depending on how well it's working for you. Talk to your prescriber if you feel gabapentin (Neurontin) isn't helping with your nerve pain. They can see how else they can help you.
                      Does gabapentin (Neurontin) help with anxiety?
                      Gabapentin (Neurontin) isn't FDA approved for anxiety. Some research suggests that it might be helpful for some people for some people, though the evidence isn't very strong. Using this medication for anxiety is considered off-label. So most prescribers usually choose other anxiety medications before considering gabapentin (Neurontin). If you have anxiety, talk to a healthcare professional about the best treatment options for you.
                      Can you take gabapentin (Neurontin) with Tylenol or ibuprofen?
                      Yes. It's generally safe to take acetaminophen (Tylenol) or ibuprofen (Advil) with gabapentin (Neurontin). These medications don't interact with gabapentin (Neurontin). But they might not be safe for everyone. For example, ibuprofen (Advil) might not be safe for people with heart or kidney problems. And acetaminophen (Tylenol) might not be the safest choice for those with liver problems. To be safe, ask a healthcare professional first if acetaminophen (Tylenol) or ibuprofen (Advil) are safe for you before taking them.
                      Is gabapentin (Neurontin) safe to take while I'm pregnant?
                      If you're pregnant or planning to get pregnant, talk to your prescriber about taking gabapentin (Neurontin). There's mixed findings about how safe it is during pregnancy. One study showed that taking gabapentin (Neurontin) early in pregnancy doesn't seem to cause serious harm to babies, except for a possible higher risk of heart problems. But taking it later on in pregnancy might raise the risk of other issues, like premature birth or low birth weight. Your prescriber can help explain the benefits and risks of taking gabapentin (Neurontin) while pregnant. They can help you decide what's safest for you and your baby.
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                      What are the risks and warnings for Gabapentin (Neurontin)?

                      Gabapentin (Neurontin) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                      risk-warning

                      Severe allergic reactions

                      Severe allergic reactions to gabapentin (Neurontin) can happen, though they're rare. These include life-threatening reactions like anaphylaxis. Reactions can cause trouble breathing or swelling of your lips, throat, or tongue.

                      Another rare but serious allergic reaction is drug reaction with eosinophilia and systemic symptom (DRESS) syndrome. Symptoms can include fever, a rash, and red skin that starts peeling. This reaction can also harm important organs in the body, like the liver, kidneys, lungs, or heart.

                      If you notice any signs of a serious allergic reaction, stop taking gabapentin (Neurontin) and get medical help right away.

                      risk-warning

                      Sleepiness, dizziness, and trouble concentrating

                      • Risk factors: Taking high doses of gabapentin (Neurontin) | Drinking alcohol | Taking other medications that can cause sleepiness

                        Gabapentin (Neurontin) can make you feel very sleepy and dizzy. It can also make it harder to think clearly or focus. These side effects usually get better after a few weeks. Make sure you know how this medication affects you before driving or doing anything that require your concentration. Tell your care team if you feel too sleepy while taking gabapentin (Neurontin).

                        Your risk of these side effects is higher if you also take other medications that cause sleepiness. They can include opioids, benzodiazepines, and muscle relaxants. Talk to your prescriber or pharmacist to make sure your medications are safe to take together.

                        risk-warning

                        Risk of suicidal thoughts and behavior

                        • Risk factors: Taking other anti-seizure medications | History of depression

                          Gabapentin (Neurontin) can raise the risk of suicidal thoughts or behavior. This is rare, but the risk can appear as early as 1 week after starting the medication.

                          Be sure you and your loved ones watch for any signs of depression or unusual changes in mood or behavior. If this happens, tell your prescriber. If you start thinking about hurting yourself, call 911 right away.

                          risk-warning

                          Higher risk of seizures and other side effects if you stop the medication too suddenly or too fast

                          • Risk factors: Taking gabapentin (Neurontin) at a high dose | Taking gabapentin (Neurontin) for a long time

                            Don't suddenly stop taking gabapentin (Neurontin) without first talking to your prescriber. Otherwise, you could have withdrawal symptoms that can be uncomfortable. This can include agitation, anxiety, restlessness, and irregular heartbeat. It can sometimes include thoughts about hurting yourself. If you take the medication to control seizures, stopping it suddenly can cause more seizures to happen.

                            If you want to stop taking gabapentin (Neurontin), let your prescriber know. They'll help lower your dose slowly, usually over at least a week, before you can stop it completely. This helps lower the risk of withdrawal.

                            risk-warning

                            Dangerously slowed breathing

                            • Risk factors: Medical conditions that cause breathing problems (e.g., COPD, asthma, head injury, high pressure in the brain) | Taking medications that can cause slow breathing

                              If you have lung problems, taking gabapentin (Neurontin) can make your breathing dangerously slow. Your breathing can also slow down if you take it with other medications that have the same effect. These medications can include benzodiazepines, opioids, and other sedatives. Very slow breathing can be serious and life-threatening.

                              Tell your prescribers and pharmacist about your health conditions and all the medications you take. They can make sure gabapentin (Neurontin) is safe for you. If needed, they might recommend to adjust your medications to keep you safe.

                              If you or anyone around you notices that you have slow or shallow breathing or trouble breathing, call 911 to get medical help right away.

                              risk-warning

                              Changes in behavior in children

                              • Risk factors: Children ages 3 to 12 years old

                                In studies, children under 12 who took gabapentin (Neurontin) for seizures sometimes had behavior changes. Some were more aggressive, had trouble concentrating, felt restless or hyper, and changes in how well they did in school. These side effects were usually mild to moderate in intensity. If you or anyone notices these changes in your child, talk to your child's prescriber.

                                dosage

                                Gabapentin (Neurontin) dosage forms

                                The average cost for 60 capsules of 300mg of Gabapentin (Neurontin) is $7.20 with a free GoodRx coupon. This is 86.45% off the average retail price of $53.13.
                                capsule
                                Capsule
                                DosageQuantityPrice as low asPrice per unit
                                100mg90 capsules$8.10$0.09
                                300mg60 capsules$7.20$0.12
                                400mg90 capsules$15.30$0.17
                                ml of oral solution
                                Ml of oral solution
                                DosageQuantityPrice as low asPrice per unit
                                250mg/5ml60 ml$7.38$0.12
                                tablet
                                Tablet
                                DosageQuantityPrice as low asPrice per unit
                                300mg30 tablets$52.34$1.74
                                600mg90 tablets$17.10$0.19
                                800mg90 tablets$17.10$0.19

                                Typical dosing for Gabapentin (Neurontin)

                                • Nerve pain from shingles

                                  • Adults: The typical dose is 300 mg by mouth once on Day 1, then 300 mg twice on Day 2, and then 300 mg three times daily starting on Day 3 and onwards. Your prescriber might raise your dose depending on your response to the medication. The maximum dose is 600 mg three times daily.

                                • Partial seizures (as add-on treatment)

                                  • Adults and children age 12 years and older: The typical starting dose is 300 mg by mouth three times daily. Your prescriber will adjust the dose based on how well it's working for you. The typical maintenance dose ranges from 300 mg to 600 mg by mouth three times daily.

                                  • Children age 5 to 11 years old: The prescriber will determine the dose based on your child's weight. The typical starting dose ranges from 10 mg/kg to 15 mg/kg daily, split into three smaller doses taken by mouth throughout the day. The typical maintenance dose is 25 mg/kg to 35 mg/kg daily, split into three smaller doses throughout the day.

                                  • Children age 3 to 4 years old: The prescriber will calculate the dose based on your child's weight. The typical starting dose ranges from 10 mg/kg to 15 mg/kg daily, split into three smaller doses taken by mouth throughout the day. The typical maintenance dose is 40 mg/kg daily, split into three smaller doses during the day.

                                Your dose might differ if you're of older age, have kidney problems, or have side effects from the medication.

                                More on Gabapentin (Neurontin) dosage forms

                                interactions

                                Interactions between Gabapentin (Neurontin) and other drugs

                                Gabapentin (Neurontin) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Gabapentin (Neurontin). Please note that only the generic name of each medication is listed below.

                                Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                                Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                                • Aluminum Carbonate, Basic
                                • Aluminum Hydroxide
                                • Aluminum Phosphate
                                • Dihydroxyaluminum Aminoacetate
                                • Dihydroxyaluminum Sodium Carbonate
                                • Ginkgo
                                • Magaldrate
                                • Magnesium Carbonate
                                • Magnesium Hydroxide
                                • Magnesium Oxide
                                • Magnesium Trisilicate
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                                alternatives

                                What are alternatives to Gabapentin (Neurontin)?

                                There are a number of medications that your doctor can prescribe in place of Gabapentin (Neurontin). Compare a few possible alternatives below.
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                                latest news

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                                Gabapentin (Neurontin) images

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                                References

                                Best studies we found

                                Amneal Pharmaceuticals LLC. (2025). Gabapentin capsule [package insert]. DailyMed.

                                Amneal Pharmaceuticals LLC. (2025). Gabapentin solution [package insert]. DailyMed.

                                Chincholkar, M. (2020). Gabapentinoids: Pharmacokinetics, pharmacodynamics and considerations for clinical practice. British Journal of Pain.

                                View All References (5)
                                GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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